Results 101 to 110 of about 157,119 (339)
Association between disruption of CD4 receptor dimerization and increased human immunodeficiency virus type 1 entry [PDF]
, 2006 Affiliation: Département de microbiologie et immunologie, Faculté de médecine, Université de Montréal & Institut de Recherches Cliniques de MontréalBACKGROUND:Human immunodeficiency virus (HIV) enters target cells by a membrane fusion process that ...
Bourgeois, Rachel +3 more
core +3 more sources
The role of CXCR4 in multiple myeloma: Cells’ journey from bone marrow to beyond
Journal of Bone Oncology, 2019 CXCR4 is a pleiotropic chemokine receptor which acts through its ligand CXCL12 to regulate diverse physiological processes. CXCR4/CXCL12 axis plays a pivotal role in proliferation, invasion, dissemination and drug resistance in multiple myeloma (MM ...
Tomalika R. Ullah
semanticscholar +1 more source
Advanced Science, EarlyView.Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen +14 more
wiley +1 more source
Anti-Tumor Effect of Celastrol on Hepatocellular Carcinoma by the circ_SLIT3/miR-223-3p/CXCR4 Axis
Cancer Management and Research, 2021 Hailong Si,1 Huiling Wang,1 Haijuan Xiao,2 Yu Fang,1 Zhaoli Wu2 1First School of Clinical Medical, Shaanxi University of Traditional Chinese Medicine, Xianyang, 712000, People’s Republic of China; 2Department of Oncology, Affiliated Hospital of the
Si H, Wang H, Xiao H, Fang Y, Wu Z
doaj
MicroRNA-409-3p regulates macrophage migration in polymyositis through targeting CXCR4
Autoimmunity, 2021 Background Macrophage migration and infiltration contribute to the pathogenesis of polymyositis (PM). This study aims to investigate the effect and underlying mechanism of miR-409-3p on macrophage migration in PM.
Qin Ye, Zhaoying Chen
doaj +1 more source
Frontiers in Immunology, 2015 Chemokines are a large family of structurally related chemoattractive cytokines, which have four conserved cysteines forming two disulfide bonds, and act through seven-transmembrane-spanning receptors coupled to heterotrimeric GTP-binding proteins (G-protein-coupled receptors).
openaire +3 more sources
CNS Neuroscience & Therapeutics, 2019 Previous studies have demonstrated that the CXCL12/CXCR4 signaling axis is involved in the regulation of neuropathic pain (NP). Here, we performed experiments to test whether the CXCL12/CXCR4 signaling pathway contributes to the pathogenesis of ...
Zhiyuan Liu +7 more
semanticscholar +1 more source
ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment
Advanced Science, EarlyView.ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song +12 more
wiley +1 more source
Hyaluronic acid alters vessel behavior in CXCL12-treated HUVECs [PDF]
, 2018 Hyaluronic acid (HA) is a key component of the extracellular matrix known for absorbing water, swelling, and altering solid stress of tumors. HA’s anionic behavior may provide important biochemical effects toward tumor progression as well.
Seibel, Alex J.
core
Hypoxic pre-conditioning increases the infiltration of endothelial cells into scaffolds for dermal regeneration pre-seeded with mesenchymal stem cells. [PDF]
, 2015 Many therapies using mesenchymal stem cells (MSC) rely on their ability to produce and release paracrine signals with chemotactic and pro-angiogenic activity.
Beegle, Julie R +6 more
core +2 more sources