Results 141 to 150 of about 142,759 (329)

Silencing of CXCR4 Inhibits Tumor Cell Proliferation and Neural Invasion in Human Hilar Cholangiocarcinoma

Gut and Liver, 2014
Background/AimsTo evaluate the expression of CXC motif chemokine receptor 4 (CXCR4) in the tissues of patients with hilar cholangiocarcinoma (hilar-CCA) and to investigate the cell proliferation and frequency of neural invasion (NI) influenced by RNAi ...
doaj   +1 more source

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1α is mediated by the chemokine receptor CXCR4 [PDF]

, 1998
Joseph Hesselgesser, Dennis D. Taub, P.V. Baskar, Michael Greenberg, James A. Hoxie, Dennis L. Kolson, Richard Horuk   +6 more
openalex   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Cyclam-Modified Polyethyleneimine for Simultaneous TGFβ siRNA Delivery and CXCR4 Inhibition for the Treatment of CCl4-Induced Liver Fibrosis

International Journal of Nanomedicine, 2021
Aftab Ullah,1 Gang Chen,2 Abid Hussain,3,4 Hanif Khan,1 Azar Abbas,5 Zhanwei Zhou,5 Muhammad Shafiq,6 Saleem Ahmad,7 Usman Ali,8 Muhammad Usman,6 Faisal Raza,8 Abrar Ahmed,8 Zijie Qiu,5 Maochao Zheng,1 Daojun Liu1 1Department of Pharmacy, Shantou ...
Ullah A, Chen G, Hussain A, Khan H, Abbas A, Zhou Z, Shafiq M, Ahmad S, Ali U, Usman M, Raza F, Ahmed A, Qiu Z, Zheng M, Liu D   +14 more
doaj  

A Simultaneous Knock-Out Knock-In Genome Editing Strategy in Hspcs Potently Inhibits Ccr5- and Cxcr4-Tropic Hiv-1 Infection

, 2023
Amanda M. Dudek, William N. Feist, Elena J. Sasu, Sofia E. Luna, Kaya Ben-Efraim, Rasmus O. Bak, Alma‐Martina Cepika, Matthew H. Porteus   +7 more
openalex   +1 more source

Tumor‐Intrinsic Forkhead Box A2 Regulates the Lymph Node Metastasis of Papillary Thyroid Carcinoma by Regulating T‐Cell Apoptosis

iLABMED, EarlyView.
We identified FOXA2 as a key regulator of lymph node metastasis in thyroid cancer, which controls cancer cell aggressiveness. FOXA2 knockdown promotes metastasis by enhancing tumor cell migration and, importantly, by inducing T‐cell apoptosis through a CCL2/LCN2‐mediated pathway. Created with BioGDP.com.
Ping Yang, Xueying Zhang, Wen Deng, Fangning Gao, Shujia Peng, Guoqiang Bao, Lijuan Yuan   +6 more
wiley   +1 more source

Cyclam-Modified Polyethyleneimine for Simultaneous TGFβ siRNA Delivery and CXCR4 Inhibition for the Treatment of CCl4-Induced Liver Fibrosis [Corrigendum]

International Journal of Nanomedicine, 2021
Ullah A, Chen G, Hussain A, et al. Int J Nanomedicine. 2021;16:4451–4470. The authors have advised there is an error in the author list on page 4451. The text “Muhammad Usman,6” should read “Muhammad Usman,8”.
Ullah A, Chen G, Hussain A, Khan H, Abbas A, Zhou Z, Shafiq M, Ahmad S, Ali U, Usman M, Raza F, Ahmed A, Qiu Z, Zheng M, Liu D   +14 more
doaj  

Targeting the CD20 and CXCR4 Pathways in Non-Hodgkin Lymphoma with Rituximab and High-Affinity CXCR4 Antagonist BKT140 [PDF]

, 2013
Katia Beider, Elena Ribakovsky, Michal Abraham, Hanna Wald, Lola Weiss, Evgenia Rosenberg, Eithan Galun, Abraham Avigdor, Orly Eizenberg, Amnon Peled, Arnon Nagler   +10 more
openalex   +1 more source

Supp Figure 2 from HIF-2α Promotes Dissemination of Plasma Cells in Multiple Myeloma by Regulating CXCL12/CXCR4 and CCR1

, 2023
Kate Vandyke, Mara N. Zeissig, D. Hewett, Sally K. Martin, Krzysztof M. Mrozik, Chee Man Cheong, Peter Dia­mond, L. Bik To, Stan Gronthos, Daniel J. Peet, Peter I. Croucher, Andrew C.W. Zannettino   +11 more
openalex   +1 more source

PD‐1/PD‐L1 in Hepatocellular Carcinoma (2014–2024): A Combined Macro and Micro Analysis of Immunotherapy Implications

iNew Medicine, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) represents a significant global health issue, with the PD‐1/PD‐L1 axis serving a pivotal target for immunotherapy in this malignancy. However, a comprehensive bibliometric analysis of PD‐1/PD‐L1 research in HCC is lacking.
Xingyu Zhu, Lin Tang, Hongyan Li, Hao Li, Jiamei Wang   +4 more
wiley   +1 more source