Results 241 to 250 of about 157,119 (339)

Inhibition of E-Selectin (GMI-1271) or E-selectin together with CXCR4 (GMI-1359) re-sensitizes multiple myeloma to therapy [PDF]

, 2019
Azab, Abdel Kareem, Azab, Feda, Fiala, Mark, Fogler, William E., King, Justin, Kohnen, Daniel, Magnani, John L., Muz, Barbara, Smith, Ted, Vij, Ravi   +9 more
core   +1 more source

Peptide Angio‐3 Attenuates Pulmonary Fibrosis Via Modulation of the Coagulation Factor Xa—Protease‐Activated Receptor‐1 Signaling Axis

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Schematic illustrating the mechanism by which the peptide Angio‐3 attenuates pulmonary fibrosis. Following lung injury, activation of the coagulation cascade via Factor Xa (FXa) signals through protease‐activated receptor‐1 (PAR‐1) to activate fibroblasts and promote fibrosis.
Dan Wang, Fei Li, Hui Chen, Bochuan Deng, Lu Cheng, Jiawen Ma, Rong Li, Lang Qu, Junqiu Xie, Ya Zhao   +9 more
wiley   +1 more source

Exploring Affordable Curative Therapy for Sickle Cell Disease in Africa: A Comprehensive Overview

American Journal of Hematology, Volume 101, Issue S1, Page 56-74, April 2026.
ABSTRACT The practical aspects of developing curative treatments for sickle cell disease (SCD) in Africa, such as gene therapy and hematopoietic stem cell transplantation, involve strengthening healthcare infrastructure, training healthcare professionals, establishing regional treatment centers, and creating national SCD programs.
Adetola A. Kassim, Alexis A. Thompson, Punam Malik   +2 more
wiley   +1 more source

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple-negative breast carcinomas. [PDF]

Oncol Lett
Li RH, Huang WH, Wu JD, Du CW, Zhang GJ.
europepmc   +1 more source

Deciphering the Impact of EPHA1‐AS1 Gene Polymorphism on Social Cognition Deficits in Parkinson's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Patients with Parkinson's disease showed poorer social cognition overall regardless of gene. There is an interplay between PD, rs2966700, and positive emotion recognition. PD patients carrying the C allele on rs2966700 performed poorer, suspected due to decreased EPHA1‐AS1 activity and increased inflammation.
Yu‐Chen Lin, Chun‐Hsiang Tan, Wei‐Pin Hong, Rwei‐Ling Yu   +3 more
wiley   +1 more source

WHIM syndrome in a child without the classic tetrad: a case confirmed by de novo CXCR4 mutation. [PDF]

Allergy Asthma Clin Immunol
Al Lohaibi R, Alotibey K, Khafaji R, Altalhi M, Alqahtani M, Alotaibi A, Goronfolah L.   +6 more
europepmc   +1 more source

Diabetic stem-cell mobilopathy [PDF]

, 2011
DiPersio, John F
core   +2 more sources

Fibrinogen‐Like Protein 2 Modulates B Cell Mucosal Immunity by Suppressing Receptor for Activated C‐Kinase 1‐Mediated AKT Phosphorylation

MedComm, Volume 7, Issue 4, April 2026.
In our study, B cells are activated with the assistance of Breg and Tfh cells, subsequently differentiating into IgA+ plasma cells. These plasma cells produce secretory IgA (sIgA) at mucosal surfaces to combat viral and parasitic infections. Mechanistically, Fgl2 directly binds to Rack1.
Jiang Chang, Da Huang, Wei Yuan, Jianing Tang, Jingzhi Yang, Yuying Chen, Zhize Yuan, Yizhi Wu, Di Wu, Weiming Yan, Qin Ning   +10 more
wiley   +1 more source

Expression of the CXCR4 S338X Variant Improves Anti-Leukemia Efficacy of Anti-CD19 CAR-T Cells. [PDF]

Cancer Sci
Mao Y, Wang X, Jin CH, Wei Z, Ding Q, Zhang KK, Dong BW, Zheng KW, Hou Y, Zhang T, Zhao WJ, Hu Z, Yang YG.   +12 more
europepmc   +1 more source

Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies

Circulation, 2017
Y. Döring, H. Noels, Emiel P. C. van der Vorst, Carlos Neideck, Virginia Egea, Maik Drechsler, Manuela Mandl, L. Pawig, Y. Jansen, K. Schröder, K. Bidzhekov, R. Megens, W. Theelen, B. Klinkhammer, P. Boor, L. Schurgers, Rick van Gorp, C. Ries, P. Kusters, A. C. van der Wal, T. Hackeng, G. Gäbel, R. Brandes, O. Soehnlein, E. Lutgens, D. Vestweber, D. Teupser, L. Holdt, D. Rader, D. Saleheen, C. Weber   +30 more
semanticscholar   +1 more source