Results 271 to 280 of about 142,759 (329)

Directional cues from CXCR4 [PDF]

Nature Reviews Immunology, 2003
openaire   +1 more source

Multi‐Omics Analysis of Human Blood Cells Reveals Unique Features of Age‐Associated Type 2 CD8 Memory T Cells

Aging Cell, Volume 25, Issue 2, February 2026.
Aging drives the accumulation of CXCR3‐ central memory CD8 T cells that exhibit Th2‐like transcriptional and epigenetic programs. These cells display a pathogenic Th2‐skewed profile and are associated with age‐related diseases, including asthma, chronic liver disease, and type 2 diabetes.
Hiroyuki Matsui, Marlene Cervantes, Mir M. Khalid, Alan Tomusiak, Varun Dwaraka, Jorge Landgrave‐Gomez, Prasanna Vadhana Ashok Kumaar, Qingwen Chen, Jessica Lasky‐Su, Jake Stone, Ritesh Tiwari, Ryan Kwok, Shuntaro Ichikawa, Benjamin D. Ambrose, Rebeccah R. Riley, Genesis Vega Hormazabal, Ariel Adkisson‐Floro, Andreea Cristina Alexandru, Ryan Smith, Birgit Schilling, Herbert G. Kasler, Eric Verdin   +21 more
wiley   +1 more source

Integrated transcriptomic and proteomic analyses identify the TLR2-CXCR4 axis as a regulator of endothelial cell migration under simulated microgravity. [PDF]

Front Physiol
Qin X, Wang R, Li C, Pan Y, Wang Y, Sun X.   +5 more
europepmc   +1 more source

HIV-1 with Multiple CCR5/CXCR4 Chimeric Receptor Use Is Predictive of Immunological Failure in Infected Children

, 2008
Mariangela Cavarelli, Ingrid Karlsson, Marisa Zanchetta, Liselotte Antonsson, Katie Piper, Carlo Giaquinto, Éva Mária Fenyõ, Anita De Rossi, Gabriella Scarlatti   +8 more
openalex   +2 more sources

Spatial Location of SPP1+TAMs and Mutually Exclusive Subsets Based on Single‐Cell and Transcriptome Data

Cancer Science, Volume 117, Issue 2, Page 548-565, February 2026.
This study indicates that SPP1, as an important regulator of tumor progression, is upregulated in various tumors and has been associated with a poor prognosis. SPP1+M2 has a unique spatial location at the forefront of tumor invasion and metastasis, thereby promoting tumor progression. MARCO+M2, which forms a mutually exclusive relationship with SPP1+M2,
Xuan Luo, JianGuo Xu, ZhiYuan Wang, XiaoFang Wang, YangHao Wang, Yu Zhang, FangFang Li, Hui Fang, XiaoYun Huang, MuYe Li, XiaoJuan Liu, JiHong Tang, PeiYang Fan, GuoJing Zhao, YongWen He, Li Bian   +15 more
wiley   +1 more source

Conjugation strategy shapes antitumor efficacy and enables dose-sparing in non-antibody protein nanoconjugates. [PDF]

Mater Today Bio
Rueda A, Garcia-Leon A, Arena LA, Mendoza JI, Aviñó A, Fabrega C, Eritja R, Paez D, Alba-Castellon L, Vazquez E, Villaverde A, Mangues R, Casanova I, Unzueta U.   +13 more
europepmc   +1 more source

Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory

Immunology, Volume 177, Issue 2, Page 254-269, February 2026.
We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco, Itziar Martín‐Ruiz, Sarai Araujo‐Aris, Diego Barriales, Janire Castelo, Leire Egia‐Mendikute, Monika Gonzalez, Jose Ezequiel Martin, Elena Molina, Maitane Mugica, Ainhoa Palacios, Iratxe Seoane, Naiara Gutiez, Estibaliz Atondo, Eneko Santos Fernández, Maddi Oyanguren, Borja Jimenez‐Lasheras, Ainize Peña‐Cearra, Ana M. Aransay, Asis Palazon, Aize Pellón, Leticia Abecia, Hector Rodriguez, Natalia Elguezabal, Juan Anguita   +24 more
wiley   +1 more source

CXCR4 Inhibitor Q-122 [PDF]

, 2020
openaire   +1 more source

TWEAK regulates the functions of hair follicle stem cells via the Fn14‐Wnt/β‐catenin‐ CXCR4 signalling axis [PDF]

Xiaoyan Zou, Yaning Tian, Lingling Peng, Mai Luo, Yan Zhu, Zihan Xue, Xiaoming Liu, Yumin Xia   +7 more
openalex   +1 more source

Exosomes in Hypertrophic Scars and Keloids: Mechanisms and Therapeutic Potentials—A Narrative Review

Journal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Hypertrophic scars and keloids, types of pathological scars, arise from dysregulated wound healing, marked by abnormal fibroblast activation and excessive extracellular matrix (ECM) deposition. Current treatments have high recurrence rates and side effects, necessitating targeted therapies. Exosomes, extracellular vesicles mediating
Mengke Wu, Jianfeng Zhang, Na Xiong, Yixiao Ma, Lingling Yong, Huaxu Liu, Qin Guo   +6 more
wiley   +1 more source