Results 41 to 50 of about 94,110 (297)
Archives of Medical Science, 2020 Introduction The aim of this study was to evaluate the effects and mechanisms of salvianolic acid B (Sal B) in preeclampsia treatment by in vivo and in vitro study. Material and methods Rats were randomly divided into 5 groups. In order to establish the
Chuanlian Zhang, Xue Han, Xiaoxue Wang
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CXCL14 is no direct modulator of CXCR4 [PDF]
FEBS Letters, 2014 C‐X‐C motif chemokine 12/C‐X‐C chemokine receptor type 4 (CXCL12/CXCR4) signaling is involved in ontogenesis, hematopoiesis, immune function and cancer. Recently, the orphan chemokine CXCL14 was reported to inhibit CXCL12‐induced chemotaxis – probably by allosteric modulation of CXCR4.
Otte, Maik +5 more
openaire +2 more sources
Extracellular Ubiquitin Enhances Autophagy and Inhibits Mitochondrial Apoptosis Pathway to Protect Neurons Against Spinal Cord Ischemic Injury via CXCR4 [PDF]
NeurospineObjective Neuronal apoptosis is considered to be a critical process in spinal cord injury (SCI). Despite growing evidence of the antiapoptotic, anti-inflammatory, and modulation of ischemic injury tolerance effects of extracellular ubiquitin (eUb ...
Hao Feng +8 more
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Indonesian Journal of Cancer, 2021 Background: Papillary thyroid carcinoma (PTC) that has metastasized has a higher risk because of the poor prognosis, ranging from decreased quality of life of the patient to death. There is a need for markers that can understand the image of the tumor so
Nurdhani Hi Djafar +2 more
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Nur77 knock-down suppresses glioma by regulating CXCR4
Archives of Medical Science, 2020 Introduction The aim of this study is to explain the effects and mechanisms of Nur77 in glioma development. Material and methods Nur77 protein and gene expression were measured by immunohistochemistry and real-time quantitative polymerase chain reaction
Yuxiang Dai +7 more
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Exploring downstream pathways of aberrantly activated kinases for targeted leukemia therapy [PDF]
, 2008 Genetic alterations resulting in uncontrolled protein tyrosine kinases (PTKs) activity are frequently found in leukemia and in human solid cancers. Although the development of small molecule kinase inhibitors has revolutionized therapy for PTKinduced ...
Gasser, Christelle
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Anti-Tumor Effect of Celastrol on Hepatocellular Carcinoma by the circ_SLIT3/miR-223-3p/CXCR4 Axis
Cancer Management and Research, 2021 Hailong Si,1 Huiling Wang,1 Haijuan Xiao,2 Yu Fang,1 Zhaoli Wu2 1First School of Clinical Medical, Shaanxi University of Traditional Chinese Medicine, Xianyang, 712000, People’s Republic of China; 2Department of Oncology, Affiliated Hospital of the
Si H, Wang H, Xiao H, Fang Y, Wu Z
doaj
Platelets, 2022 Stromal cell-derived factor 1 (SDF-1, also known as CXCL12) and its receptor CXCR4 have shown to play a role in the homing and engraftment of hematopoietic stem and progenitor cells.
Yi Li +5 more
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A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction [PDF]
, 2008 Feline immunodeficiency virus (FIV) targets helper T cells by attachment of the envelope glycoprotein (Env) to CD134, a subsequent interaction with CXCR4 then facilitating the process of viral entry.
Margaret J Hosie +14 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source