Results 41 to 50 of about 88,749 (308)
Journal of Blood Medicine, 2023 Marie M Plante,1 ErinMarie O Kimbrough,2 Amit K Agarwal,3 Liuyan Jiang,4 Kirk Bourgeois,4 Greta C Stamper,5 Michael W Stewart,6 Han W Tun2 1Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA; 2Division of Hematology and Oncology, Mayo ...
Plante MM +7 more
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The role of the chemokine receptor CXCR4 in infection with feline immunodeficiency virus [PDF]
, 1999 Infection with feline immunodeficiency virus (FIV) leads to the development of a disease state similar to AIDS in man. Recent studies have identified the chemokine receptor CXCR4 as the major receptor for cell culture-adapted strains of FIV, suggesting ...
Hosie, M.J., Willett, B.J.
core +1 more source
CXCL12 and CXCR4 as Potential Early Biomarkers for Luminal A and Luminal B Subtypes of Breast Cancer
Cancer Management and Research, 2023 Joanna Motyka,1 Ewa Gacuta,2 Aleksandra Kicman,3 Monika Kulesza,1 Paweł Malinowski,4 Sławomir Ławicki1 1Department of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, Bialystok, Poland ...
Motyka J +5 more
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Chronic inflammation evoked by pathogenic stimulus during carcinogenesis
4 open, 2019 A pathogenic (biological or chemical) stimulus is the earliest information received by a cell that can result in the disruption of homeostasis with consequent development of disease.
Brücher Björn L.D.M., Jamall Ijaz S.
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CXCR4-targeted theranostics in oncology
European Journal of Nuclear Medicine and Molecular Imaging, 2022 AbstractA growing body of literature reports on the upregulation of C-X-C motif chemokine receptor 4 (CXCR4) in a variety of cancer entities, rendering this receptor as suitable target for molecular imaging and endoradiotherapy in a theranostic setting.
Buck, Andreas K. +8 more
openaire +3 more sources
CXCL14 is no direct modulator of CXCR4 [PDF]
FEBS Letters, 2014 C‐X‐C motif chemokine 12/C‐X‐C chemokine receptor type 4 (CXCL12/CXCR4) signaling is involved in ontogenesis, hematopoiesis, immune function and cancer. Recently, the orphan chemokine CXCL14 was reported to inhibit CXCL12‐induced chemotaxis – probably by allosteric modulation of CXCR4.
Otte, Maik +5 more
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CXCR4: A virus’s best friend? [PDF]
Infection, Genetics and Evolution, 2014 Viruses are dependent on their hosts for replication and dispersal in the environment; thus, the most successful viruses are those that co-evolve with their hosts. CXCR4 is a cellular chemokine receptor that plays central roles in development, hematopoiesis, and immune surveillance through signaling induced by its ligand, CXCL12.
Kathleen L, Arnolds, Juliet V, Spencer
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Does the Chemotherapy Protocol Affect CXCL12/CXCR4 Axes in Acute Myeloid Leukemia Patients with Monocytic Differentiation? [PDF]
Middle East Journal of Cancer, 2022 Background: The CXCR4 receptor along with CXCL12 is believed to have an effect on the onset, progression, migration, and treatment complications and improve acute myeloid leukemia (AML) treatment outcomes.
Bahar Yazdani +4 more
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CXCR4 as a novel target in immunology: moving away from typical antagonists [PDF]
, 2022 CXCR4 has been a target of interest in drug discovery for numerous years. However, so far, most if not all studies focused on finding antagonists of CXCR4 function.
Milligan, Graeme +13 more
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Cells, 2019 Stromal cell-derived factor 1 (SDF-1) and its main receptor, CXC chemokine receptor 4 (CXCR4), play a critical role in endothelial cell function regulation during cardiogenesis, angiogenesis, and reendothelialization after injury. The expression of CXCR4
Jong-Ik Heo +6 more
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