Results 21 to 30 of about 3,649 (185)

Virtual Prospection of Marine Cyclopeptides as Therapeutics by Means of Conceptual DFT and Computational ADMET

open access: yesPharmaceuticals, 2022
Bioactive peptides are chemical compounds created through the covalent bonding of amino acids, known as amide or peptide bonds. Due to their unusual chemistry and various biological effects, marine bioactive peptides have garnered considerable research ...
Norma Flores-Holguín   +2 more
doaj   +1 more source

Chemical Classification of Cyclic Depsipeptides

open access: yesCurrent Protein & Peptide Science, 2017
Cyclic depsipeptides (CDPs) are a family of cyclic peptide-related compounds, of which the ring is mainly composed of amino- and hydroxy acid residues joined by amide and ester bonds (at least one), leading to a wide diversity of fascinating chemical structures. They differ in both their ring structure and their side chains, especially by the nature of
Taevernier, Lien   +3 more
openaire   +3 more sources

Cyclic Octamer Peptoids: Simplified Isosters of Bioactive Fungal Cyclodepsipeptides

open access: yesMolecules, 2018
Cyclic peptoids have recently emerged as an important class of bioactive scaffolds with unique conformational properties and excellent metabolic stabilities.
Assunta D’Amato   +5 more
doaj   +1 more source

Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae. [PDF]

open access: yes, 2017
Natural product screening programs have uncovered molecules from diverse natural sources with various biological activities and unique structures. However, much is yet underexplored and additional information is hidden in these exceptional collections ...
Ackermann, Gail   +14 more
core   +3 more sources

Metabolities from Marine Sponges of the Genus Callyspongia: Occurrence, Biological Activity, and NMR Data

open access: yesMarine Drugs, 2021
The genus Callyspongia (Callyspongiidae) encompasses a group of demosponges including 261 described species, of which approximately 180 have been accepted after taxonomic reviews.
Lucas Hilário Nogueira de Sousa   +4 more
doaj   +1 more source

Exploring bioactive properties of marine cyanobacteria Isolated from the Portuguese coast: high potential as a source of anticancer compounds [PDF]

open access: yes, 2013
The oceans remain a major source of natural compounds with potential in pharmacology. In particular, during the last few decades, marine cyanobacteria have been in focus as producers of interesting bioactive compounds, especially for the treatment of ...
Barreiro, Aldo   +9 more
core   +2 more sources

From amino acid sequence to bioactivity: the biomedical potential of antitumor peptides [PDF]

open access: yes, 2016
Chemoprevention is the use of natural and/or synthetic substances to block, reverse, or retard the process of carcinogenesis. In this field, the use of antitumor peptides is of interest as, (i) these molecules are small in size, (ii) they show good cell ...
Ando   +75 more
core   +1 more source

Enhanced Ohmyungsamycin A Production via Adenylation Domain Engineering and Optimization of Culture Conditions

open access: yesFrontiers in Microbiology, 2021
Ohmyungsamycins (OMSs) A and B are cyclic depsipeptides produced by marine Streptomyces strains, which are synthesized by a non-ribosomal peptide synthetase. Notably, OMS A exhibits more potent activity against Mycobacterium tuberculosis and human cancer
Eunji Kim   +5 more
doaj   +1 more source

Antiviral activity of animal venom peptides and related compounds [PDF]

open access: yes, 2017
Viruses exhibit rapid mutational capacity to trick and infect host cells, sometimes assisted through virus-coded peptides that counteract host cellular immune defense.
Mata, Élida Cleyse Gomes da Mata   +3 more
core   +2 more sources

The mycotoxin definition reconsidered towards fungal cyclic depsipeptides

open access: yesJournal of Environmental Science and Health, Part C, 2016
Currently, next to the major classes, cyclic depsipeptides beauvericin and enniatins are also positioned as mycotoxins. However, as there are hundreds more fungal cyclic depsipeptides already identified, should these not be considered as mycotoxins as well?
Lien, Taevernier   +4 more
openaire   +2 more sources

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