Biological activities of ethanolic extracts from deep-sea antarctic marine sponges [PDF]
, 2013 We report on the screening of ethanolic extracts from 33 deep-sea Antarctic marine sponges for different biological activities. We monitored hemolysis, inhibition of acetylcholinesterase, cytotoxicity towards normal and transformed cells and growth ...
Ambrožič Avguštin, Jerneja +9 more
core +3 more sources
Peptides from Marine-Derived Fungi: Chemistry and Biological Activities
Marine Drugs, 2023 Marine natural products are well-recognized as potential resources to fill the pipeline of drug leads to enter the pharmaceutical industry. In this circumstance, marine-derived fungi are one of the unique sources of bioactive secondary metabolites due to
Salar Hafez Ghoran +4 more
doaj +1 more source
Identification of Four New agr Quorum Sensing-Interfering Cyclodepsipeptides from a Marine Photobacterium [PDF]
, 2013 During our search for new natural products from the marine environment, we discovered a wide range of cyclic peptides from a marine Photobacterium, closely related to P. halotolerans.
Anita Nielsen +7 more
core +2 more sources
Metabolomics reveals the heterogeneous secretome of two entomopathogenic fungi to ex vivo cultured insect tissues. [PDF]
PLoS ONE, 2013 Fungal entomopathogens rely on cellular heterogeneity during the different stages of insect host infection. Their pathogenicity is exhibited through the secretion of secondary metabolites, which implies that the infection life history of this group of ...
Charissa de Bekker +3 more
doaj +1 more source
Cyclodepsipeptides from Marine Sponges: Natural Agents for Drug Research
Marine Drugs, 2010 A number of natural products from marine sponges, such as cyclodepsipeptides, have been identified. The structural characteristics of this family of cyclic peptides include various unusual amino acid residues and unique N-terminal polyketide-derived ...
Rosa Lemmens-Gruber +1 more
doaj +1 more source
Production of destruxins from Metarhizium spp. fungi in artificial medium and in endophytically colonized cowpea plants. [PDF]
PLoS ONE, 2014 Destruxins (DTXs) are cyclic depsipeptides produced by many Metarhizium isolates that have long been assumed to contribute to virulence of these entomopathogenic fungi.
Patrícia S Golo +8 more
doaj +1 more source
Engineering of Aspergillus niger for the production of secondary metabolites [PDF]
, 2014 Background: Filamentous fungi can each produce dozens of secondary metabolites which are attractive as therapeutics, drugs, antimicrobials, flavour compounds and other high-value chemicals.
Boecker, Simon +7 more
core +1 more source
Marine Drugs, 2019 Lagunamide D, a new cytotoxic macrocyclic depsipeptide, was discovered from a collection of marine cyanobacteria from Loggerhead Key in the Dry Tortugas, Florida.
Danmeng Luo +4 more
doaj +1 more source
Unraveling the senses of Phytophthora; leads to novel control strategies? [PDF]
, 2009 Oomycetes cause devastating diseases on plants and animals. They cause major yield losses in many crop plants and their control heavily depends on agrochemicals. This is certainly true for the potato late blight pathogen Phytophthora infestans.
Govers, F. +4 more
core +2 more sources
Marine Drugs, 2009 Investigation of an extract from the marine cyanobacterium Lyngbya semiplena, collected in Tumon Bay, Guam, led to the identification of three new cyclodepsipeptides, lyngbyastatins 8–10 (1–3).
Hendrik Luesch +3 more
doaj +1 more source