Results 81 to 90 of about 3,649 (185)

Nonribosomal peptides, key biocontrol components for Pseudomonas fluorescens In5, isolated from a Greenlandic suppressive soil. [PDF]

, 2015
UnlabelledPotatoes are cultivated in southwest Greenland without the use of pesticides and with limited crop rotation. Despite the fact that plant-pathogenic fungi are present, no severe-disease outbreaks have yet been observed.
Dorrestein, Pieter C, Glaring, Mikkel A, Kersten, Roland, Koyama, Nobuhiro, Michelsen, Charlotte F, Stougaard, Peter, Watrous, Jeramie   +6 more
core  

Total Synthesis of the Marine Cyclic Depsipeptide Lagunamide D

Marine Drugs
Lagunamide D is a structurally distinct 26-membered cytotoxic cyclic depsipeptide, originally isolated from a marine cyanobacterium. It exhibits potent antiproliferative activity in the low nanomolar range against A549 human lung adenocarcinoma cells and HCT116 colon cancer cells.
Huiru Nan, Xiong-En Long, Jianfei He, Hailiang Xing, Min-Jing Cheng, Jin-Bao Peng, Tao Ye, Jia-Lei Yan, Junyang Liu   +8 more
openaire   +3 more sources

Asymmetric Strategies for the Synthesis of Enantiopure α‐/β‐/γ‐Thio‐Carboxylic Acids Bearing a Stereocentre at CS Bond

Advanced Synthesis &Catalysis, Volume 367, Issue 18, September 29, 2025.
Enantioenriched α‐/β‐/γ‐thiocarboxylic acids featuring C–S chirality are valuable targets in organic synthesis. This review outlines recent progress in their asymmetric synthesis, including chiral pool approaches, metal‐ /organo‐catalysis, and emerging biocatalytic strategies. Enantiomerically pure α‐/β‐/γ‐thiocarboxylic acids bearing a stereocentre at
Jingyue Wu, Daniele Castagnolo
wiley   +1 more source

Cryptophycin unit B analogues

Beilstein Journal of Organic Chemistry
Drug conjugates using toxic payloads are a promising approach for selectively combating cancer while sparing healthy tissue. The lack of highly cytotoxic and at the same time selective therapeutics against cancer is an ongoing challenge.
Thomas Schachtsiek, Jona Voss, Maren Hamsen, Beate Neumann, Hans-Georg Stammler, Norbert Sewald   +5 more
doaj   +1 more source

Corals as Source of Bacteria with Antimicrobial Activity [PDF]

, 2008
In this study we examined marine bacteria associated with different corals (Porites lutea, Galaxea fascicularis, Acropora sp. and Pavona sp.) collected from vicinity of Panjang island, Jepara, North Java Sea, Indonesia for their antimicrobial activities ...
Imhoff, J. F. (Johannes), radjasa, O. (ocky), Sabdono, A. (Agus), Wiese, J. (Jutta)   +3 more
core  

Recombination and selectional forces in cyanopeptolin NRPS operons from highly similar, but geographically remote strains [PDF]

, 2008
Background Cyanopeptolins are nonribosomally produced heptapetides showing a highly variable composition. The cyanopeptolin synthetase operon has previously been investigated in three strains from the genera Microcystis, Planktothrix and ...
Rounge, Trine B, Rohrlack, Thomas, Kristensen, Tom, Jakobsen, Kjetill S   +3 more
core   +2 more sources

Hijacking the Electron Train: Menaquinone‐Binding Antimicrobial Peptides

ChemBioChem, Volume 26, Issue 18, September 18, 2025.
Menaquinone is an emerging target for antimicrobial peptides. Could it be the new Achilles’ Heel of bacteria? The rise of antibiotic resistance threatens to undermine modern medicine, making the development of new antibiotics and novel targets an urgent priority.
Eilidh J. Matheson, Stephen A. Cochrane
wiley   +1 more source

Design and Synthesis of a Novel N-(1H-tetrazol-5-yl)methyl Cyclic Peptoid Using Nosyl-protected N-(1-trityl-1H-tetrazol-5-yl)methyl Substituted Glycine [PDF]

, 2017
: A solid phase synthesis of a cyclic peptoid bearing (1H-tetrazol-5-yl)methyl as N-substituent has been developed employing the monomer approach.
Krishnamurthy, M., Narendra, N., Prabhu, G., Samarasimhareddy, M., Sureshbabu, V.V.   +4 more
core   +1 more source

Arthogalin, a Cyclic Depsipeptide from the Lichen Arthothelium galapagoense

Zeitschrift für Naturforschung B, 1995
The structure and stereochemistry of arthogalin from the liehen Arthothelium galapagoense has been elucidated as the cyclic depsipeptide 1′.
S. Huneck, U. Himmelreich, G. Nicholson
openaire   +1 more source

Mycosis Fungoides, Sézary Syndrome, and Cutaneous B‐Cell Lymphomas: 2025 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, Volume 100, Issue 9, Page 1603-1628, September 2025.
ABSTRACT Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease classification is based on histopathologic review and immunohistochemical staining of an appropriate skin ...
Alexandra C. Hristov, Trilokraj Tejasvi, Ryan A. Wilcox   +2 more
wiley   +1 more source