Results 241 to 250 of about 72,449 (334)

Synthetic Biology and Biomaterials Strategies to Deceive the Tumor Microenvironment in CAR‐T Immunotherapy

open access: yesSmall, EarlyView.
A. Synthetic biology and biomaterials have emerged as tools to study and facilitate the treatment of solid tumors wi‐th chimeric antigen receptor‐CAR‐T cells. These strategies aim to resist the tumor microenvironment‐TME that presents cellular, biochemical, and mechanical immunosuppressive signals that hinder CAR‐T efficacy. B.
Grazia Marsico   +2 more
wiley   +1 more source

Understanding of endo/lysosomal escape of nanomaterials in biomedical application

open access: yesSmart Molecules, EarlyView.
This review summarized mainstream mechanisms of endo/lysosomal escape and design strategies of endo/lysosomal escapable nanoparticles in view of surface charge, polarity & hydrophobicity, particle morphology, and lysosomal escape agents. The utilization of endo/lysosomal escapable nanoparticles for vaccine delivery and genetic engineering are ...
Xin Wang   +3 more
wiley   +1 more source

From Molecules to Bioaggregates: Unraveling the Photoexcitation Dynamics of Intracellularly Self‐Assembled Thiophene‐Based Fibers

open access: yesSmall Science, EarlyView.
Cell‐guided self‐assembly of thiophene based molecules inside living cells produces photostable, biocompatible nanofibers exhibiting J‐like excitonic coupling and stimulated emission. Integrated spectroscopic and quantum‐chemical analyses reveal unique photophysical behavior and low phototoxicity, positioning these supramolecular structures as ...
Filippo Monti   +11 more
wiley   +1 more source

Time‐Domain Visualization of Electron‐Phonon Coupling in Nanographenes

open access: yesSmall Methods, EarlyView.
Impulsive vibrational spectroscopy, Raman spectroscopy, and density functional theory calculations are gathered together to unveil elusive low‐frequency collective vibrational modes in dibenzo[hi,st]ovalene nanographenes, enabling the detailed comparison between vibrational modes in derivatives with different peripheral groups.
Rafael Muñoz‐Mármol   +13 more
wiley   +1 more source

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