Results 41 to 50 of about 492,044 (389)
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway.
Proceedings of the National Academy of Sciences of the United States of America, 1999 beta-Catenin plays a dual role in the cell: one in linking the cytoplasmic side of cadherin-mediated cell-cell contacts to the actin cytoskeleton and an additional role in signaling that involves transactivation in complex with transcription factors of ...
M. Shtutman +6 more
semanticscholar +1 more source
The crystal structure of cyclin A [PDF]
Structure, 1995 Eukaryotic cell cycle progression is regulated by cyclin dependent protein kinases (CDKs) whose activity is regulated by association with cyclins and by reversible phosphorylation. Cyclins also determine the subcellular location and substrate specificity of CDKs.
Brown NR +8 more
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Bisphosphonate inhibits the expression of cyclin A2 at the transcriptional level in normal human oral keratinocytes. [PDF]
, 2017 Nitrogen-containing bisphosphonates (N-BPs) are the most widely used anti-resorptive agents in the treatment of bone-related diseases. N-BPs inhibit bone resorption by specifically targeting osteoclasts, bone-resorbing cells.
Kang, Mo K +5 more
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Frontiers in Microbiology, 2021 Codon usage bias (the preferential use of certain synonymous codons (optimal) over others is found at the organism level (intergenomic) within specific genomes (intragenomic) and even in certain genes.
Loreto Arias +7 more
doaj +1 more source
Translational control of cyclins [PDF]
Cell Division, 2011 Regulation of cyclin levels is important for many cell cycle-related processes and can occur at several different steps of gene expression. Translational regulation of cyclins, which occurs by a variety of regulatory mechanisms, permits a prompt response to signal transduction pathways induced by environmental stimuli.
Ming-Chih Lai, Woan-Yuh Tarn
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Cyclin D1-mediated microRNA expression signature predicts breast cancer outcome [PDF]
, 2018 Background: Genetic classification of breast cancer based on the coding mRNA suggests the evolution of distinct subtypes. Whether the non-coding genome is altered concordantly with the coding genome and the mechanism by which the cell cycle directly ...
Addya, Sankar +16 more
core +2 more sources
Biologia Plantarum, 2013 Daucus carota is cultivated widely but grows best in cool climates. Suppression subtractive hybridization (SSH) is a PCR based method used to selectively amplify differentially expressed cDNAs and simultaneously suppress non-target cDNA.
S. R. Kumar +4 more
doaj +1 more source
Frontiers in Plant Science, 2022 The D-type cyclin (CYCD) gene, as the rate-limiting enzyme in the G1 phase of cell cycle, plays a vital role in the process of plant growth and development. Early studies on plant cyclin mostly focused on herbs, such as Arabidopsis thaliana.
Zhongnan Zhao +6 more
doaj +1 more source
Distinct properties of cyclin-dependent kinase complexes containing cyclin A1 and cyclin A2 [PDF]
Biochemical and Biophysical Research Communications, 2009 The distinct expression patterns of the two A-type cyclins during spermatogenesis and the absolute requirement for cyclin A1 in this biological process in vivo suggest that they may confer distinct biochemical properties to their CDK partners. We therefore compared human cyclin A1- and cyclin A2-containing CDK complexes in vitro by determining kinetic ...
Vaidehi Jobanputra +3 more
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Asynchronous nuclear division cycles in multinucleated cells [PDF]
, 2006 Synchronous mitosis is common in multinucleated cells. We analyzed a unique asynchronous nuclear division cycle in a multinucleated filamentous fungus, Ashbya gossypii.
Gladfelter, A. S. +2 more
core +2 more sources