Results 201 to 210 of about 13,616,352 (396)

Alternate cyclin D1 mRNA splicing modulates P27\u3csup\u3eKlP1\u3c/sup\u3e binding and cell migration [PDF]

open access: yes, 2008
Cyclin D1 is an important cell cycle regulator but in cancer its overexpression also increases cellular migration mediated by p27KlP1 stabilization and RhoA inhibition.
Casimiro, Mathew C.   +7 more
core   +1 more source

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu   +13 more
wiley   +1 more source

Optimal bounds for a Gaussian Arithmetic-Geometric type mean by quadratic and contraharmonic means [PDF]

open access: yesarXiv, 2018
In this paper, we present the best possible parameters $\alpha_i, \beta_i\ (i=1,2,3)$ and $\alpha_4,\beta_4\in(1/2,1)$ such that the double inequalities \begin{align*} \alpha_1Q(a,b)+(1-\alpha_1)C(a,b)&
arxiv  

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

open access: yesAdvanced Science, EarlyView.
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei   +11 more
wiley   +1 more source

Alterations in TP53, cyclin D2, c-Myc, p21WAF1/CIP1 and p27KIP1 expression associated with progression in B-CLL

open access: yesFolia Histochemica et Cytobiologica, 2010
B-cell chronic lymphocytic leukaemia (B-CLL) originates from B lymphocytes that may differ in the activationlevel, maturation state or cellular subgroups in peripheral blood. Tumour progression in CLL B cells seems to result in gradualaccumulation of the
Antosz Halina   +4 more
doaj  

Refinements of the inequalities between Neuman-Sandor, arithmetic, contra-harmonic and quadratic means [PDF]

open access: yesarXiv, 2012
In this paper, we prove that the inequalities $\alpha [1/3 Q(a,b)+2/3 A(a,b)]+(1-\alpha)Q^{1/3}(a,b)A^{2/3}(a,b)0$ with $
arxiv  

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