Results 61 to 70 of about 90,181 (143)

Brucine Inhibits the Proliferation of Human Lung Cancer Cell Line PC-9 
via Arresting Cell Cycle

Chinese Journal of Lung Cancer, 2014
Background and objective It has been proven that Cyclin D1 and Cyclin E are the important positive regulators of cell cycle, they are closely related to the tumor proliferation. The aim of this study is to explore the relationship between Brucine and the
Miao LI, Ping LI, Mei ZHANG, Feng MA, Li SU   +4 more
doaj   +1 more source

The Difference in the Cyclin D1 Expression in Advanced Stage Nasopharyngeal Cancer based on Treatment Response: A Retrospective Cohort Study

Acta Medica Indonesiana, 2020
Background: nasopharyngeal cancer (NPC) is the most common type of head and neck cancer in Indonesia (28.4%). Reports showed that 18.9% of cases came with advanced stage. Chemotherapy play important role in advanced stage. However, patients with the same
Cosphiadi Irawan, Rahmat Cahyanur, Lisnawati Lisnawati, Murdani Abdullah, Reyhan Eddy Yunus   +4 more
doaj   +2 more sources

Expression of cyclin D1 in clear cell sarcoma of kidney. Is it useful in differentiating it from its histological mimics?

Diagnostic Pathology, 2019
Background Clear cell sarcoma of the kidney (CCSK) is a rare malignant pediatric renal neoplasm with a heterogeneous histological appearance which often results in misdiagnosis.
Nasir Uddin, Khurram Minhas, Jamshid Abdul-Ghafar, Arsalan Ahmed, Zubair Ahmad   +4 more
doaj   +1 more source

Cyclin D1 expression in acute leukemia

Hematology, 2006
Disorders of the cell cycle regulatory machinery play a key role in the pathogenesis of cancer. Over expression of cyclin D1 protein has been reported in several solid tumors and certain lymphoid malignancies, but little is known about the involvement of cyclin D1 in acute leukemia.In this study, we analyzed the expression of cyclin D1 at protein level
Salah, Aref, M, Mabed, M, El-Sherbiny, T, Selim, A, Metwaly   +4 more
openaire   +2 more sources

Cyclin D1 Overexpression in Laryngeal Carcinomas.

Nippon Jibiinkoka Gakkai Kaiho, 1998
Overexpression of cyclin D1 has been found in a variety of malignancies and is suggested to be related to tumor progression. We immunohistochemically investigated the overexpression of cyclin D1 protein in 92 laryngeal carcinomas. Twenty-eight (30.4%) of the carcinoma specimens showed overexpression of cyclin D1.
X F, Wang, T, Nakashima, M, Masuda, K, Matsui, T, Yamamoto, S, Komiyama   +5 more
openaire   +3 more sources

Cyclin D1 expression in colorectal cancer is a favorable prognostic factor in men but not in women in a prospective, population-based cohort study

Biology of Sex Differences, 2011
Background Although colorectal cancer (CRC) is generally not considered to be a hormone-dependent malignancy, several sex-related differences in incidence, molecular characteristics and survival have been reported.
Wangefjord Sakarias, Manjer Jonas, Gaber Alexander, Nodin Björn, Eberhard Jakob, Jirström Karin   +5 more
doaj   +1 more source

Prognostic significance of cyclin D1 protein expression and gene amplification in invasive breast carcinoma.

PLoS ONE, 2017
The oncogenic capacity of cyclin D1 has long been established in breast cancer. CCND1 amplification has been identified in a subset of patients with poor prognosis, but there are conflicting data regarding the predictive value of cyclin D1 protein ...
Angela B Ortiz, Diego Garcia, Yolanda Vicente, Magda Palka, Carmen Bellas, Paloma Martin   +5 more
doaj   +1 more source

Evaluation of Cyclin D1 protein and its association with the clinicopathological characteristics and prognosis of lung cancer: A retrospective study from Southern Kerala, India

Lung India
Background Cyclin D1 is a protein that can enhance the proliferation of cancer cells and has been detected in various malignancies, including lung cancer. However, routine examinations for Cyclin D1 in lung cancer cases have not been conducted in Kerala.
Neeraja Panakkal, Asha Lekshmi, Jagathnath K. K. M. Nair, Kunjuraman Sujathan   +3 more
doaj   +1 more source

Cyclin D1 Splice Variants [PDF]

Journal of Biological Chemistry, 2003
David A. Solomon, Ying Wang, Sejal R. Fox, Tah C. Lambeck, Sarah Giesting, Zhengdao Lan, Adrian M. Senderowicz, Erik S. Knudsen   +7 more
openaire   +1 more source

Role of cyclin D1 in breast carcinoma

Journal of Research in Medical Sciences, 2013
Background: Breast carcinoma is the most frequent cancer among women with considerable invasive and metastatic behavior. CCND1, the oncogene encoding cyclin D1, is amplified in a substantial proportion of human cancers.
Fereshteh Mohammadizadeh, Mohsen Hani, Mohammad Ranaee, Marzie Bagheri   +3 more
doaj