Results 1 to 10 of about 111,564 (289)

Translational control of cyclins [PDF]

open access: yesCell Division, 2011
Regulation of cyclin levels is important for many cell cycle-related processes and can occur at several different steps of gene expression. Translational regulation of cyclins, which occurs by a variety of regulatory mechanisms, permits a prompt response
W. Tarn, M. Lai
semanticscholar   +6 more sources

Identification of Arabidopsis Meiotic Cyclins Reveals Functional Diversification among Plant Cyclin Genes [PDF]

open access: yesPLoS Genetics, 2013
Meiosis is a modified cell division in which a single S-phase is followed by two rounds of chromosome segregation resulting in the production of haploid gametes.
P. Bulánková   +3 more
semanticscholar   +2 more sources

Living with or without cyclins and cyclin-dependent kinases. [PDF]

open access: yesGenes & Development, 2004
Entry into, progression through, and exit from the G1 phase of the mammalian cell cycle in response to extracellular mitogenic cues are presumed to be governed by cyclin-dependent kinases (Cdks) regulated by the D-type and E-type cyclins.
C. Sherr, James M. Roberts
semanticscholar   +3 more sources

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. [PDF]

open access: greenMolecular and Cellular Biology, 1994
Conditional overexpression of human cyclins B1, D1, and E was accomplished by using a synthetic cDNA expression system based on the Escherichia coli tetracycline repressor. After induction of these cyclins in asynchronous Rat-1 fibroblasts, a decrease in
D. Resnitzky   +3 more
semanticscholar   +2 more sources

Cell cyclins: triggering elements of cancer or not?

open access: yesWorld Journal of Surgical Oncology, 2010
Cyclins are indispensable elements of the cell cycle and derangement of their function can lead to cancer formation. Recent studies have also revealed more mechanisms through which cyclins can express their oncogenic potential. This review focuses on the
M. Stamatakos   +6 more
semanticscholar   +3 more sources

The Less Known Cyclins—Uncovered

open access: yesApplied Sciences, 2021
Cyclins belong to a group of proteins that are cyclically produced and destructed in a cell. Cyclins are a family of proteins that are a key component of the cell cycle regulating system, which level of expression depends on the phase of the cycle ...
Agnieszka Żuryń   +4 more
doaj   +1 more source

In vivo assessment of simultaneous G1 cyclins silencing by a tumor-specific bidirectional promoter on the mammary tumor in nude mice

open access: yesFrontiers in Veterinary Science, 2022
Dysregulation of G1 cyclins (cyclins D1 A and E) expression contributes to the loss of standard cell cycle control during tumorigenesis. This study aims to evaluate the inhibitory effect of G1 cyclins in nude mice.
Gholamreza Mesbah   +6 more
doaj   +1 more source

Viral cyclins mediate separate phases of infection by integrating functions of distinct mammalian cyclins. [PDF]

open access: yesPLoS Pathogens, 2012
Gammaherpesvirus cyclins have expanded biochemical features relative to mammalian cyclins, and promote infection and pathogenesis including acute lung infection, viral persistence, and reactivation from latency.
Katherine S Lee   +5 more
doaj   +1 more source

The Hunt for Cyclin [PDF]

open access: yesCell, 2008
It is 25 years since Tim Hunt discovered cyclin, the oscillating protein that drives activation of cyclin-dependent kinases and entry into mitosis (Evans et al., 1983).
Peter K. Jackson, Peter K. Jackson
openaire   +4 more sources

Home - About - Disclaimer - Privacy