Viral cyclins mediate separate phases of infection by integrating functions of distinct mammalian cyclins. [PDF]
PLoS Pathogens, 2012 Gammaherpesvirus cyclins have expanded biochemical features relative to mammalian cyclins, and promote infection and pathogenesis including acute lung infection, viral persistence, and reactivation from latency.
Katherine S Lee +5 more
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Two-way communication between cell cycle and metabolism in budding yeast: what do we know?
Frontiers in Microbiology, 2023 Coordination of cell cycle and metabolism exists in all cells. The building of a new cell is a process that requires metabolic commitment to the provision of both Gibbs energy and building blocks for proteins, nucleic acids, and membranes.
Yanfei Zhang +5 more
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Emerging Mechanisms of G1/S Cell Cycle Control by Human and Mouse Cytomegaloviruses
mBio, 2021 Cytomegaloviruses (CMVs) are among the largest pathogenic viruses in mammals. To enable replication of their long double-stranded DNA genomes, CMVs induce profound changes in cell cycle regulation.
Boris Bogdanow +2 more
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Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction [PDF]
The EMBO Journal, 2000 The key regulator of G(2)-M transition of the cell cycle is M-phase promoting factor (MPF), a complex composed of cdc2 and a B-type cyclin. Cyclin B1 nuclear localization involves phosphorylation within a region called the cytoplasmic retention signal, which also contains a nuclear export signal.
Kong, Monica +3 more
openaire +4 more sources
Prediction of Cyclin Protein Using Two-Step Feature Selection Technique
IEEE Access, 2020 Cyclins are a family of proteins that regulate the cell cycle by activating cyclin-dependent kinases or a group of enzymes required in the cell cycle. Constructing a model to classify Cyclins is of importance to understand their function. It is urgent to
Jia-Nan Sun +6 more
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AaCycTL Regulates Cuticle and Trichome Development in Arabidopsis and Artemisia annua L.
Frontiers in Plant Science, 2021 Artemisinin is an important drug for resistance against malaria. Artemisinin is derived from the glandular trichome of leaves, stems, or buds of the Chinese traditional herb Artemisia annua.
Boran Dong +15 more
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Cyclins and cyclin-dependent kinases: a biochemical view. [PDF]
Biochemical Journal, 1995 J. Pines
semanticscholar +3 more sources
Frontiers in Plant Science, 2023 IntroductionThe leaf, the main product organ, is an essential factor in determining the Chinese cabbage growth, yield and quality.MethodsTo explore the regulatory mechanism of leaf size development of Chinese cabbage, we investigated the leaf size ...
Lixia Wang +11 more
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Cells, 2022 Pancreatic cancer is a leading cause of cancer mortality and is projected to become the second-most common cause of cancer mortality in the next decade. While gene-wide association studies and next generation sequencing analyses have identified molecular
Cristina Di Giorgio +16 more
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LIN-9 phosphorylation on threonine-96 is required for transcriptional activation of LIN-9 target genes and promotes cell cycle progression. [PDF]
PLoS ONE, 2014 Cell cycle transitions are governed by the timely expression of cyclins, the activating subunits of Cyclin-dependent kinases (Cdks), which are responsible for the inactivation of the pocket proteins.
Frank Eckerdt +2 more
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