Results 41 to 50 of about 579 (162)
A new member of the fusaricidin family – structure elucidation and synthesis of fusaricidin E
Beilstein Journal of Organic Chemistry, 2017 Two hitherto unknown fusaricidins were obtained from fermentation broths of three Paenibacillus strains. After structure elucidation based on tandem mass spectrometry and NMR spectroscopy, fusaricidin E was synthesized to confirm the structure and the ...
Marcel Reimann +5 more
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Total synthesis of the marine cyanobacterial cyclodepsipeptide apratoxin A [PDF]
Proceedings of the National Academy of Sciences, 2004 A total synthesis of apratoxin A was developed. Apratoxin A, isolated from Lyngbya spp. cyanobacteria, is representative of a growing class of marine cyanobacterial cyclodepsipeptides wherein discrete polypeptide and polyketide domains are merged by ester and amide or amide-derived linkages ...
Jiehao, Chen, Craig J, Forsyth
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Synthesis of a Carbon‐Linked Acyldepsipeptide Derivative
European Journal of Organic Chemistry, Volume 29, Issue 15, 22 April 2026.The synthesis of a methylene‐linked acyldepsipeptide (ADEP) is reported. Success relied upon an improve method to generate a versatile vinyl glycine methyl ester synthon and a rationally optimized Grubb’s metathesis. NMR and in silico studies revealed an unusual trans–trans proline orientation for this new unnatural ADEP analog, advancing the ...
Katelyn G. Stevens-Davis +6 more
wiley +1 more source
Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)
ELECTROPHORESIS, Volume 47, Issue 1, Page 106-136, January 2026.ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
wiley +1 more source
Synthesis and Biological Activities of Cyclodepsipeptides of Aurilide Family from Marine Origin
Marine Drugs, 2021 Aurilides are a class of depsipeptides occurring mainly in marine cyanobacteria. Members of the aurilide family have shown to exhibit strong cytotoxicity against various cancer cell lines.
Synthia Michon +2 more
doaj +1 more source
Cryptophycins: cytotoxic cyclodepsipeptides with potential for tumor targeting [PDF]
Journal of Peptide Science, 2017 Cryptophycins are a class of 16‐membered highly cytotoxic macrocyclic depsipeptides isolated from cyanobacteria. The biological activity is based on their ability to interact with tubulin. They interfere with microtubule dynamics and prevent microtubules from forming correct mitotic spindles, which causes cell‐cycle arrest and apoptosis.
Weiss, Christine +3 more
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Marine Drugs, 2009 Investigation of an extract from the marine cyanobacterium Lyngbya semiplena, collected in Tumon Bay, Guam, led to the identification of three new cyclodepsipeptides, lyngbyastatins 8–10 (1–3).
Hendrik Luesch +3 more
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Synthesis of PF1022A, an anthelmintic cyclodepsipeptide.
The Journal of Antibiotics, 1994 Anthelmintic cyclodepsipeptide PF1022A has been prepared in eleven steps from N-Boc-N-methyl-L-leucine, benzyl 3-phenyl-D-lactate and benzyl D-lactate.
F E, Dutton, S J, Nelson
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Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 5, September 2025.ABSTRACT Enniatins (ENNs) are emerging mycotoxins mainly produced by Fusarium species. They frequently contaminate cereals and cereal‐based products. Despite their widespread occurrence, these mycotoxins are not yet regulated, but concerns about their potential health effects due to dietary exposure exist.
France Coulet +3 more
wiley +1 more source
Marine Drugs, 2014 Bioassay-guided fractionation of a culture extract of Beauveria felina EN-135, an entomopathogenic fungus isolated from a marine bryozoan, led to the isolation of a new cyclodepsipeptide, iso-isariin D (1); two new O-containing heterocyclic compounds ...
Feng-Yu Du +4 more
doaj +1 more source