Results 41 to 50 of about 577 (161)

Stereocontrol in Conformationally Stable C(sp2)─C(sp3) Atropisomers

open access: yesAngewandte Chemie, Volume 137, Issue 28, July 7, 2025.
Building in our expertize in the synthesis of trans‐dihydrobenzofurans via organocatalyzed domino Michael/O‐cyclization between β‐naphthols and nitroalkenes, we developed an efficient strategy to access a new family of atropisomers bearing a conformationally stable C(sp2)─C(sp3) bond and two stereogenic centers through simple and highly ...
Antoine Domain   +10 more
wiley   +2 more sources

A new member of the fusaricidin family – structure elucidation and synthesis of fusaricidin E

open access: yesBeilstein Journal of Organic Chemistry, 2017
Two hitherto unknown fusaricidins were obtained from fermentation broths of three Paenibacillus strains. After structure elucidation based on tandem mass spectrometry and NMR spectroscopy, fusaricidin E was synthesized to confirm the structure and the ...
Marcel Reimann   +5 more
doaj   +1 more source

Synthesis of PF1022A, an anthelmintic cyclodepsipeptide.

open access: yesThe Journal of Antibiotics, 1994
Anthelmintic cyclodepsipeptide PF1022A has been prepared in eleven steps from N-Boc-N-methyl-L-leucine, benzyl 3-phenyl-D-lactate and benzyl D-lactate.
F E, Dutton, S J, Nelson
openaire   +3 more sources

Cryptophycins: cytotoxic cyclodepsipeptides with potential for tumor targeting [PDF]

open access: yesJournal of Peptide Science, 2017
Cryptophycins are a class of 16‐membered highly cytotoxic macrocyclic depsipeptides isolated from cyanobacteria. The biological activity is based on their ability to interact with tubulin. They interfere with microtubule dynamics and prevent microtubules from forming correct mitotic spindles, which causes cell‐cycle arrest and apoptosis.
Weiss, Christine   +3 more
openaire   +3 more sources

Calcaripeptides A–C, Cyclodepsipeptides from a Calcarisporium Strain

open access: yesJournal of Natural Products, 2013
The isolation and structure elucidation of the novel calcaripeptides A (1), B (2), and C (3) and studies on their biosynthetic origin are described. The calcaripeptides were identified from Calcarisporium sp. strain KF525, which was isolated from the German Wadden Sea.
Johanna Silber   +4 more
openaire   +5 more sources

Synthesis of a Carbon‐Linked Acyldepsipeptide Derivative

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 15, 22 April 2026.
The synthesis of a methylene‐linked acyldepsipeptide (ADEP) is reported. Success relied upon an improve method to generate a versatile vinyl glycine methyl ester synthon and a rationally optimized Grubb’s metathesis. NMR and in silico studies revealed an unusual trans–trans proline orientation for this new unnatural ADEP analog, advancing the ...
Katelyn G. Stevens-Davis   +6 more
wiley   +1 more source

Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)

open access: yesELECTROPHORESIS, Volume 47, Issue 1, Page 106-136, January 2026.
ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
wiley   +1 more source

Synthesis and Biological Activities of Cyclodepsipeptides of Aurilide Family from Marine Origin

open access: yesMarine Drugs, 2021
Aurilides are a class of depsipeptides occurring mainly in marine cyanobacteria. Members of the aurilide family have shown to exhibit strong cytotoxicity against various cancer cell lines.
Synthia Michon   +2 more
doaj   +1 more source

Lyngbyastatins 8–10, Elastase Inhibitors with Cyclic Depsipeptide Scaffolds Isolated from the Marine Cyanobacterium Lyngbya semiplena

open access: yesMarine Drugs, 2009
Investigation of an extract from the marine cyanobacterium Lyngbya semiplena, collected in Tumon Bay, Guam, led to the identification of three new cyclodepsipeptides, lyngbyastatins 8–10 (1–3).
Hendrik Luesch   +3 more
doaj   +1 more source

Enniatin Mycotoxins in Food: A Systematic Review of Global Occurrence, Biosynthesis, and Toxicological Impacts on In Vitro Human Cell Models

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 5, September 2025.
ABSTRACT Enniatins (ENNs) are emerging mycotoxins mainly produced by Fusarium species. They frequently contaminate cereals and cereal‐based products. Despite their widespread occurrence, these mycotoxins are not yet regulated, but concerns about their potential health effects due to dietary exposure exist.
France Coulet   +3 more
wiley   +1 more source

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