Results 11 to 20 of about 207,862 (335)

Correlation of COX- 2 Expression in Colorectal Carcinoma with Clinicopathological Features [PDF]

open access: yesTürk Patoloji Dergisi, 2017
Objective: Colorectal carcinoma is the most common neoplasm of the gastrointestinal tract. COX-2 expression is upregulated in colorectal carcinoma. Therefore its assessment would identify patients amenable to adjuvant anticyclooxygenase therapy.
Sandhya VENKATACHALA, Manjula RAJENDRAN
doaj   +1 more source

Genetic Variants in COX2 and ALOX Genes and Breast Cancer Risk in White and Black Women

open access: yesFrontiers in Oncology, 2021
COX and ALOX genes are involved in inflammatory processes and that may be related to breast cancer risk differentially between White and Black women. We evaluated distributions of genetic variants involved in COX2 and ALOX-related pathways and examined ...
Jennifer M. Mongiovi   +10 more
doaj   +1 more source

Cyclooxygenase enzyme and PGE2 expression in patients with functional and non-functional pituitary adenomas

open access: yesBMC Endocrine Disorders, 2020
Background Pituitary adenomas as multifactorial intracranial neoplasms impose a massive burden of morbidity on patients and characterizing the molecular mechanism underlying their pathogenesis has received considerable attention.
Nasrin Akbari   +9 more
doaj   +1 more source

Fabrication of Celecoxib PVP Microparticles Stabilized by Gelucire 48/16 via Electrospraying for Enhanced Anti-Inflammatory Action

open access: yesPharmaceuticals, 2023
Electrospraying (ES) technology is considered an efficient micro/nanoparticle fabrication technique with controlled dimensions and diverse morphology.
Samar Zuhair Alshawwa   +5 more
doaj   +1 more source

Cyclooxygenase‐2 in epilepsy [PDF]

open access: yesEpilepsia, 2013
SummaryEpilepsy is one of the more prevalent neurologic disorders in the world, affecting approximately 50 million people of different ages and backgrounds. Epileptic seizures propagating through both lobes of the forebrain can have permanent debilitating effects on a patient's cognitive and somatosensory brain functions.
Nadia Lelutiu   +6 more
openaire   +2 more sources

Triterpenoid and Coumarin Isolated from Astilbe grandis with Anti-Inflammatory Effects through Inhibiting the NF-κB Pathway in LPS-Induced RAW264.7 Cells

open access: yesMolecules, 2023
The roots of Astilbe grandis, known as “Ma sang gou bang”, are used as a Miao traditional medicine with anti-inflammatory and analgesic properties. However, the active components and mechanism of action of this plant remain mostly uncharacterized.
Jin-Fang Luo   +6 more
doaj   +1 more source

Treatment with paracetamol, ketorolac or etoricoxib did not hinder alveolar bone healing: a histometric study in rats

open access: yesJournal of Applied Oral Science, 2010
Prostaglandins control osteoblastic and osteoclastic function under physiological or pathological conditions and are important modulators of the bone healing process.
Ricardo Nogueira Fracon   +3 more
doaj   +1 more source

Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling

open access: yesFrontiers in Oncology, 2020
Pyruvate kinase M2 (PKM2) is a key enzyme of glycolysis, which is highly expressed in many tumor cells, and has emerged as an important player in tumor progression and metastasis.
Wenjing Guo   +14 more
doaj   +1 more source

Nimesulide limits kainate-induced oxidative damage in the rat hippocampus [PDF]

open access: yes, 2000
Kainate induces a marked expression of cyclooxygenase-2 after its systemic administration. Because cyclooxygenase-2 activity is associated to the production of reactive oxygen species, we investigated the effects of nimesulide, a selective cyclooxygenase-
Ajamieh, Hussam   +4 more
core   +1 more source

COX2 expression is associated with proliferation and tumor extension in vestibular schwannoma but is not influenced by acetylsalicylic acid intake

open access: yesActa Neuropathologica Communications, 2019
Acetylsalicylic acid has been linked to a lower risk for different cancer types, presumably through its inhibitory effect on cyclooxygenase 2.
Felix Behling   +9 more
doaj   +1 more source

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