Results 231 to 240 of about 995,042 (360)

Influence of Cyclooxygenase-2 Inhibitors on Kynurenic Acid Production in Rat Brain in Vitro. [PDF]

Neurotox Res, 2019
Zakrocka I, Targowska-Duda KM, Wnorowski A, Kocki T, Jóźwiak K, Turski WA.   +5 more
europepmc   +1 more source

Effects of cyclooxygenase-2 inhibitors on cell proliferation and cell death in human hematopoietic cancer cell lines

, 2011
Cyril Sobolewski
openalex   +1 more source

Prostacyclin Synthase Gene Transfer Modulates Cyclooxygenase-2–Derived Prostanoid Synthesis and Inhibits Neointimal Formation in Rat Balloon-Injured Arteries [PDF]

, 2002
Michiharu Yamada, Yasushi Numaguchi, Kenji Okumura, Mitsunori Harada, Keiji Naruse, Hideo Matsui, Takayuki Ito, Tetsuo Hayakawa   +7 more
openalex   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

The cost‐effectiveness of aspirin versus cyclooxygenase‐2‐selective inhibitors for colorectal carcinoma chemoprevention in healthy individuals [PDF]

, 2004
Chin Hur, Lee S. Simon, G. Scott Gazelle
openalex   +1 more source

Risk of Death or Reinfarction Associated With the Use of Selective Cyclooxygenase-2 Inhibitors and Nonselective Nonsteroidal Antiinflammatory Drugs After Acute Myocardial Infarction

Circulation, 2006
G. Gislason, S. Jacobsen, J. Rasmussen, S. Rasmussen, P. Buch, J. Friberg, T. K. Schramm, S. Z. Abildstrom, L. Køber, M. Madsen, C. Torp-Pedersen   +10 more
semanticscholar   +1 more source

Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F‐Actin Formation and Facilitate Double‐strand DNA Breaks Repair in TMZ‐Resistant Glioblastoma

Advanced Science, EarlyView.
This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang, Wanxiang Niu, Yuanfei Wang, Peng Chen, Maolin Mu, Xiaoming Zhang, Ben Xu, Shanshan Hu, Chaoshi Niu, Pengfei Wu   +9 more
wiley   +1 more source

Synthesis, Biological Evaluation, and Enzyme Docking Simulations of 1,5-Diarylpyrrole-3-Alkoxyethyl Ethers as Selective Cyclooxygenase-2 Inhibitors Endowed with Anti-inflammatory and Antinociceptive Activity

, 2008
Maurizio Anzini, Michele Rovini, Andrea Cappelli, Salvatore Vomero, Fabrizio Manetti, Maurizio Botta, Lidia Sautebin, Antonietta Rossi, Carlo Pergola, Carla Ghelardini, Monica Norcini, Antonio Giordani, Francesco Makovec, Paola Anzellotti, Paola Patrignani, Mariangela Biava   +15 more
openalex   +1 more source

Cyclooxygenase-2 inhibitors and cardiovascular risk in a nation-wide cohort study after the withdrawal of rofecoxib.

European Heart Journal, 2012
M. Bäck, Li Yin, E. Ingelsson
semanticscholar   +1 more source

Increased Blood Flow and Tendon Swelling Precedes Vascular Expansion and Tissue Matrix Changes In Early Human Tendinopathy: A Potential Window for Superior Treatment Response

Advanced Science, EarlyView.
Human participants with early‐ or chronic‐stage tendinopathy and healthy controls are investigated using ultrasound Doppler, 3T and 7T MRI, and tendon biopsies. Tendon swelling and hyperperfusion are evident early, while vascular growth and extracellular matrix changes are most pronounced in chronic tendinopathy. Early intervention may provide superior
Max F. R. Merkel, Nikolaj M. Malmgaard‐Clausen, Marius Lendal, Hartwig R. Siebner, René B. Svensson, Stephanie G. Dakin, Marcus Krüger, Luisa Schmidt, Jakob Agergaard, Ching‐Yan Chloé Yeung, S. Peter Magnusson, Michael Kjaer   +11 more
wiley   +1 more source