Results 91 to 100 of about 35,749 (233)

Piscirickettsiosis in Farmed Turbot, Scophthalmus maximus

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Piscirickettsia salmonis is a well‐established intracellular pathogen of farmed Atlantic salmon around the world. The bacterium has also been detected from a number of other hosts including lumpfish (Cyclopterus lumpus), seabass (Dicentrarchus labrax) and rainbow trout (Oncorhynchus mykiss).
Hanne K. Nilsen   +9 more
wiley   +1 more source

Discovery and molecular basis of subtype-selective cyclophilin inhibitors

open access: yes, 2022
Although cyclophilins are attractive targets for probing biology and therapeutic intervention, no subtype-selective cyclophilin inhibitors have been described.
Chan, Alix I.   +11 more
core   +1 more source

Soluble expression of recombinant cyclophilin A in Escherichia coli

open access: yes浙江大学学报. 农业与生命科学版, 2010
To produce a large amount of soluble cyclophilin A (CypA) protein, the recombinant pRSET -CypA plasmid was transferred into E. coli BL21. Using the 2×YT culture medium, the medium compositions of carbon source, nitrogen source and ampicillin ...
YAN Xiao   +3 more
doaj   +1 more source

Physiology and Transcriptomics Reveal Divergent Strategies of Mycorrhiza‐Mediated Drought Adaptation in Poplar

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Mycorrhizal symbiosis shapes plant growth and stress resilience. Here, we compared physiological and molecular responses of poplars (P. x canescens) colonised by Paxillus involutus (Pi) or Cenococcum geophilum (Cg) under control conditions, drought stress and recovery.
Huili Shi, Zhuchou Lu, Andrea Polle
wiley   +1 more source

Microarray Gene Expression Analysis of Lesional Skin in Canine Vesicular Cutaneous Lupus Erythematosus (VCLE)

open access: yesVeterinary Dermatology, EarlyView.
Background: Vesicular cutaneous lupus erythematosus (VCLE) is a rare autoimmune disease in dogs and is considered the canine counterpart of human subacute cutaneous lupus erythematosus (SCLE). However, the molecular mechanisms underlying VCLE remain incompletely defined.
Treasa Clifford   +5 more
wiley   +1 more source

Cyclophilin Inhibition by a (Z)-Alkene cis-Proline Mimic

open access: yes, 2016
Cyclophilin Inhibition by a (Z)-Alkene cis-Proline ...
Scott A. Hart (2722963)   +1 more
core   +1 more source

Unlocking the Door to Neuronal Woes in Alzheimer’s Disease: Aβ and Mitochondrial Permeability Transition Pore

open access: yesPharmaceuticals, 2010
Mitochondrial dysfunction occurs early in the progression of Alzheimer’s disease. Amyloid-β peptide has deleterious effects on mitochondrial function and contributes to energy failure, respiratory chain impairment, neuronal apoptosis, and generation of ...
Heng Du, Shirley ShiDu Yan
doaj   +1 more source

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin   +7 more
wiley   +1 more source

A partial length cyclophilin-encoding (cyp) cDNA isolated from Ganoderma boninense

open access: yes, 2011
Oil palm is sub­jected to var­i­ous pests and dis­eases, one of the most impor­tant being basal stem rot (BSR) dis­ease which is caused by a few species of Gan­o­derma. Gan­o­derma is a white rot fun­gus that attacks oil palm around the world.
Shaharuddin, Noor Azmi   +5 more
core  

Inhibition of calcineurin by cyclosporin A-cyclophilin requires calcineurin B

open access: yes, 1992
The interaction of the immunosuppressive complex cyclosporin A-cyclophilin (CsA-CyP) with the Ca2+/calmodulin-dependent protein phosphatase calcineurin is investigated using a recombinant form of the A subunit of calcineurin (rCNA).
Timothy L. Born   +7 more
core   +1 more source

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