Results 111 to 120 of about 32,096 (206)
Veterinary Dermatology, Volume 37, Issue 4, Page 478-487, August 2026.Background: Vesicular cutaneous lupus erythematosus (VCLE) is a rare autoimmune disease in dogs and is considered the canine counterpart of human subacute cutaneous lupus erythematosus (SCLE). However, the molecular mechanisms underlying VCLE remain incompletely defined.
Treasa Clifford +5 more
wiley +1 more source
HeliyonIntroduction: No markers have been used to diagnose historical peritoneal dialysis (PD)-related peritonitis. Cyclophilin A (CypA) is associated with glucose toxicity and inflammation.
Shang-Feng Tsai +3 more
doaj +1 more source
Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury
The Journal of Physiology, Volume 604, Issue 16, Page 6659-6674, 15 August 2026.Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich +5 more
wiley +1 more source
Cyclophilin A in Cardiovascular Homeostasis and Diseases
The Tohoku Journal of Experimental Medicine, 2015 Vascular homeostasis is regulated by complex interactions between many vascular cell components, including endothelial cells, vascular smooth muscle cells (VSMCs), adventitial inflammatory cells, and autonomic nervous system. The balance between oxidant and antioxidant systems determines intracellular redox status, and their imbalance can cause ...
openaire +3 more sources
PharmaceuticsBackground: Inflammatory bowel diseases (IBDs) have several treatment modalities including immunoregulators, like cyclosporine A, an immunosuppressant that interacts with cytoplasmic cyclophilin A, and probiotics.
Laura Dosh +8 more
doaj +1 more source
Molecular Characterization of Cyclophilin Protein Gene in Skin Normal Microflora: Malassezia furfur
Iranian Journal of Public Health, 2009 Background: Malassezia are dimorphic, lipid-dependent yeasts, which are responsible for causing several cutaneous and systemic conditions. Although cyclophilins (CyPs) are highly conserved cytosolic proteins that catalyze the peptidyl-prolyl cis-trans ...
M Moazeni +7 more
doaj
Sanglifehrin A mitigates multiorgan fibrosis by targeting the collagen chaperone cyclophilin B
JCI InsightPathological deposition and crosslinking of collagen type I by activated myofibroblasts drives progressive tissue fibrosis. Therapies that inhibit collagen synthesis have potential as antifibrotic agents.
Hope A. Flaxman +13 more
doaj +1 more source
Cyclophilin D at the Heart of Neonatal Hypoxia. [PDF]
JACC Basic Transl SciGordon JW.
europepmc +1 more source