Results 31 to 40 of about 30,484 (184)
MxB sensitivity of HIV-1 is determined by a highly variable and dynamic capsid surface
eLife, 2020 The type one interferon induced restriction factor Myxovirus resistance B (MxB) restricts HIV-1 nuclear entry evidenced by inhibition of 2-LTR but not linear forms of viral DNA.
Richard J Miles +5 more
doaj +1 more source
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Biotechnology & Biotechnological Equipment, 2019 The aim of this study was to investigate the effects of cyclophilin B on MC3T3-E1 cells and the underlying mechanism. CCK-8 assay was used to evaluate the cell activity, polymerase chain reaction to verify the overexpression of cyclophilin B, western ...
Fan Mei, Yanhong Tu
doaj +1 more source
BMC Research Notes, 2012 Background Hyperelastosis cutis is an inherited autosomal recessive connective tissue disorder. Affected horses are characterized by hyperextensible skin, scarring, and severe lesions along the back. The disorder is caused by a mutation in cyclophilin B.
Boudko Sergei P +5 more
doaj +1 more source
A vaccine to prevent initial loss of cognition and eventual Alzheimer's disease in elderly persons
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021 Prevention is better than cure and prevention of Alzheimer's disease (AD) may be possible. In elderly persons who are cognitively normal, synaptic hypometabolism as shown by reduced cerebral uptake of fluorodeoxyglucose (18F‐FDG), provides a premonitory ...
Jeffrey Fessel
doaj +1 more source
Expression and role of cyclophilin B in stomach cancer
Genetics and Molecular Research, 2015 We elucidated the expression of ciclosporin protein B (cyclophilin B) in stomach cancer tissue and the correlation between cyclophilin B and clinicopathological parameters, and determined the effect of cyclophilin B on growth and proliferation of stomach cancer cells.
D Q, Meng, P L, Li, M, Xie
openaire +2 more sources
PLoS ONE, 2021 Whitefly, Bemisia tabaci (Gennadius) is an important pest of cotton causing direct damage as sap feeder and vector of Cotton leaf curl virus (CLCuV). Previous few studies suggest that female whiteflies are more efficient vector of begomovirusthan males ...
Ikbalpreet Singh +4 more
doaj +1 more source
Cyclosporine inhibits a direct interaction between cyclophilins and hepatitis C NS5A.
PLoS ONE, 2010 BackgroundHepatitis C Virus (HCV) infection is a leading indication for liver transplantation. HCV infection reoccurs almost universally post transplant, decreasing both graft longevity and patient survival.
Fiona Fernandes +2 more
doaj +1 more source
Role of Cyclophilin B in Prolactin Signal Transduction and Nuclear Retrotranslocation [PDF]
Molecular Endocrinology, 2000 The pleiotropic actions of PRL are necessary for mammary growth and differentiation and in vitro lymphoid proliferation. The proximal action of this ligand is mediated by its cell surface receptor via associated networks. PRL action, however, is also associated with the internalization and translocation of this hormone into the nucleus.
M A, Rycyzyn +3 more
openaire +2 more sources
SIV replication in human cells
Frontiers in Microbiology, 2012 Current human immunodeficiency virus type 1 (HIV-1) pandemic is believed to originate from cross-species transmission of simian immunodeficiency virus (SIV) into human population.
Hiroaki eTakeuchi, Ryuta eSakuma
doaj +1 more source