Results 31 to 40 of about 1,092 (168)
Archiv der Pharmazie, Volume 355, Issue 11, November 2022., 2022 Significant effort has been invested into the development of cholinesterase reactivators that are capable of treating organophosphorus poisoning. A series of 12 coumarin derivatives equipped with linker‐connected nonaromatic terminal amino moieties were prepared in this study.
Paul W. Elsinghorst +6 more
wiley +1 more source
Acta Medica, 2006 In this work, in vitro potency of novel serie of monoquaternary pyridinium oximes to reactivate cyclosarin-inhibited acetylcholinesterase (AChE) was tested.
Kamil Kuča, Jan Pícha, Daniel Jun
doaj +1 more source
Molecules, 2007 Preparation of 1-(4-hydroxy-iminomethylpyridinium)-3-pyridiniumpropane dibromide is described. This compound represents a new acetylcholinesterase (AChE) reactivator, which has no substituents on the second pyridinium ring as found in other commonly used
Jan Marek +6 more
doaj +1 more source
Raman efficiency in the middle ultraviolet band for G‐series nerve agents and sulfur mustard
Journal of Raman Spectroscopy, Volume 53, Issue 1, Page 69-81, January 2022., 2022 UV Raman spectroscopy can be applied for rapid, selective detection of hazardous substances such as small droplets of low volatile CWA. In the present report, the Raman target efficiency of selected features has been evaluated for multiple excitation wavelengths ranging from 210 to 330 nm.
Fredrik Kullander, Lars Landström
wiley +1 more source
Repeated low-dose organophosphate DFP exposure leads to the development of depression and cognitive impairment in a rat model of Gulf War Illness [PDF]
, 2016 Approximately 175,000 to 250,000 of the returning veterans from the 1991 Persian Gulf War exhibit chronic multi-symptom illnesses that includes neurologic co-morbidities such as depression, anxiety and cognitive impairments.
Deshpande, Laxmikant, Phillips, Kristin
core +2 more sources
Droplet Microfluidics and Directed Evolution of Enzymes: An Intertwined Journey
Angewandte Chemie, Volume 133, Issue 46, Page 24572-24591, November 8, 2021., 2021 From bulk emulsification to on‐chip droplet formation and sorting, droplet microfluidics offers numerous tools for high‐throughput screening. Directed evolution has greatly benefitted from these technological advances over the last twenty years. This review article gives a chronological overview of in vivo directed evolution of enzymes facilitated by ...
Ariane Stucki +3 more
wiley +1 more source
Acta Medica, 2005 1. The efficacy of the oxime HLö-7 and currently used oximes (pralidoxime, obidoxime, HI-6) to reactivate acetylcholinesterase inhibited by various nerve agents (sarin, tabun, cyclosarin, VX) was tested by in vitro methods. 2. Both H oximes (HLö-7, HI-6)
Kamil Kuča +4 more
doaj +1 more source
Chemical Weapons in the Iran-Iraq War (1980–1988). 4. The Destruction of Iraqi Chemical Weapons
Вестник войск РХБ защиты, 2020 After the defeat of Iraqi army in Kuwait in February 1991, on April 3, the UN Security Council (UN Security Council) adopted Resolution 687, that «decides that Iraq shall unconditionally accept the destruction, removal, or rendering harmless, under ...
M. V. Supotnitskiy +2 more
doaj +1 more source
Acta Medica, 2004 The oxime K005 [1,3–bis(2–hydroxyiminomethylpyridinium) propane dibromide] for the reactivation of the enzyme acetylcholinesterase (AChE) inhibited by cyclosarin and VX was tested.
Kamil Kuča, Vlastimil Dohnal
doaj +1 more source
Вестник войск РХБ защиты, 2021 One of the ways to ensure high reliability of detection, identification and accuracy of quantitative determination of toxic chemicals (TC) in environmental and biomedical samples by gas and liquid chromatography-mass spectrometry methods is to use ...
V. А. Yashkir +6 more
doaj +1 more source