Molecules, 2007 Preparation of 1-(4-hydroxy-iminomethylpyridinium)-3-pyridiniumpropane dibromide is described. This compound represents a new acetylcholinesterase (AChE) reactivator, which has no substituents on the second pyridinium ring as found in other commonly used
Jan Marek +6 more
doaj +1 more source
Raman efficiency in the middle ultraviolet band for G‐series nerve agents and sulfur mustard
Journal of Raman Spectroscopy, Volume 53, Issue 1, Page 69-81, January 2022., 2022 UV Raman spectroscopy can be applied for rapid, selective detection of hazardous substances such as small droplets of low volatile CWA. In the present report, the Raman target efficiency of selected features has been evaluated for multiple excitation wavelengths ranging from 210 to 330 nm.
Fredrik Kullander, Lars Landström
wiley +1 more source
New group of xylene linker-containing acetylcholinesterase reactivators as antidotes against the nerve agent cyclosarin [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2006 Nerve agents such as sarin, cyclosarin and tabun are organophosphorus substances able to inhibit the enzyme acetylcholinesterase (AChE; EC 3.1.1.7). AChE reactivators and anticholinergics are generally used as antidotes in the case of intoxication with these agents.
Martina, Hrabinova +3 more
openaire +2 more sources
Boron nitride nanoclusters as a sensor for Cyclosarin nerve agent: DFT and thermodynamics studies [PDF]
SN Applied Sciences, 2020 To find a chemical sensor for detection of Cyclosarin (GF) nerve agent, we studied its interaction with B24N24, AlB23N24, B16N16 and AlB15N16 nanoclusters by means of density functional theory calculations. All calculations were investigated whit the M06 method and 6-311G(d,p) basis set.
Karim Derakhshan Karjabad +4 more
openaire +1 more source
Assessing the Clinical Features and Blood Biochemistries of Acute Organophosphorus Chemical Warfare Agents in Iranian Veterans [PDF]
, 2021 Background: Nerve Agents (NAs) are a chemical weapons, and their use is prohibited. They were used for numerous-times in the warfare of Iraq against Iran.
Agin, Khosrow, Mostafazadeh, Babak
core +2 more sources
Colorimetric Stimuli-Responsive Hydrogel Polymers for the Detection of Nerve Agent Surrogates [PDF]
, 2015 The threat of chemical warfare agents (CWAs) necessitates the development of functional materials that not only quickly detect the presence of CWAs but also actively protect against their toxicity.
Ahmed, Eilaf +3 more
core +2 more sources
Examination of effectiveness of chemical scavengers as therapeutics in organophosphate poisoning [PDF]
, 2017 Cholinergic crisis triggered by inhibition of cholinesterases via organophosphorus nerve agents (OP) and pesticides is treated with atropine and a reactivator of inhibited cholinesterase, called oxime.
Bierwisch, Anne
core +2 more sources
Detection of Chemical Weapon Agents Using Spectroscopic Probes: A Computational Study
Journal of Chemistry, 2020 Organophosphorus compounds are organic compounds widely employed in agriculture as well as in chemical weapons. The use in agriculture is due to their insecticidal properties.
Letícia S. Braga +5 more
doaj +1 more source
Real‐time remote detection of airborne chemical hazards – an unmanned aerial vehicle (UAV) carrying an ion mobility spectrometer [PDF]
, 2023 Rapidly detecting and identifying chemical agents after a chemical release is crucial for a reliable assessment of imminent risks and provides the initial basis for defining an adequate level of protection for first responders.
Ahrens, Andre +9 more
core +1 more source
Arhiv za higijenu rada i toksikologiju, 2007 This paper describes an in vitro study of three potential acetylcholinesterase (AChE; EC 3.1.1.7) reactivators derived from a monoquaternary reactivator pralidoxime. Compounds used were pyridinium-2-aldoxime-4-carbamoyl-N-methyl iodide (TO231), pyridinium-2-aldoxime-4-ethoxycarbonyl-N-methyl iodide (TO237), and pyridinium-2-aldoxime-5-ethoxycarbonyl-N ...
Veronika, Racakova +3 more
openaire +2 more sources