Results 61 to 70 of about 687 (168)
Effects of low-level sarin and cyclosarin exposure on white matter integrity in Gulf War Veterans [PDF]
We previously found evidence of reduced gray and white matter volume in Gulf War (GW) veterans with predicted low-level exposure to sarin (GB) and cyclosarin (GF). Because loss of white matter tissue integrity has been linked to both gray and white matter atrophy, the current study sought to test the hypothesis that GW veterans with predicted GB/GF ...
Linda L, Chao +2 more
openaire +2 more sources
A green density functional theory‐based Raman prediction workflow is presented as a safe alternative to hazardous experimental characterization. The optimized computational model enables accurate spectral prediction, scalable database expansion, and structural differentiation using key P═O, C═N, and P–F Raman markers while minimizing waste and ...
Honghyun Kim +3 more
wiley +1 more source
Therapeutic Efficacy of Different Antidotal Mixtures Against Poisoning with GF-Agent in Mice
The toxicity of cyclohexyl methylphosphonofluoridate (GF-agent; cyclosarin) and therapeutic efficacy of four oximes (trimedoxime, methoxime, obidoxime and HI-6) in combination with atropine or benactyzine (BNZ) was studied in mice.
Lucie Bartošová +3 more
doaj +1 more source
Micro/nanorobots for detecting and eliminating biological and chemical warfare agents
Fuel‐powered and field‐driven micro/nanorobots provide a cutting‐edge platform to safeguard national security and defense. This review reports the latest research progress in micro/nanorobots in sensing and detoxifying biological and chemical warfare agents.
Song Li +4 more
wiley +1 more source
Toxicological analyses of the bone matrix: Successes and challenges
Abstract This study aimed to conduct an in‐depth and systematic literature review dealing with toxicological analyses on human bone tissue and focusing on the forensic toxicological and archaeotoxicological field. Several studies have focused their research on medical drugs, drugs of abuse, and trace elements on both human cadavers and skeletal remains,
Gaia Giordano +3 more
wiley +1 more source
Substituted Monoquaternary Oximes as Reactivators of Cyclosarin- and Chlorpyrifos-Inhibited Acetylcholinesterase [PDF]
U ovome in vitro istraživanju testiran je reaktivacijski potencijal triju reaktivatora acetilkolinesteraze (AChE; EC 3.1.1.7) dobivenih iz monokvaternog reaktivatora pralidoksima.
Jun, Daniel +3 more
core +1 more source
A Thermostable Bacterial Metallohydrolase that Degrades Organophosphate Plasticizers
This bacterial enzyme, cyclase‐phosphotriesterase (C‐PTE) from Ruegeria pomeroyi DSS‐3, shows significant potential for breaking down organophosphate pollutants. Beyond its capability to hydrolyze specific plasticizers such as triphenyl phosphate and tris(2‐chloropropyl) phosphate, C‐PTE's crystal structure reveals a binuclear zinc active site, and it ...
Dawei Ji +5 more
wiley +1 more source
The inactivation of acetylcholinesterase (AChE) by organophosphorus agent (OP) compounds is a serious problem regardless of how the individual was exposed.
Jeffry D. Madura (1335309) +3 more
core +1 more source
Two is better than one. The introduction of a second hydroxamic acid substituents along the cavity of a sulfonatocalix[4]arene improves the activity with which this compound detoxifies highly toxic nerve agents of the V‐type to such an extent that its use as an antidote is now conceivable.
Patrick Gaß +3 more
wiley +1 more source
The biocatalyzed oxidative detoxification of the V‐series simulant PhX with the microperoxidase AcMP11 affords the corresponding phosphonothioate as the prominent product instead of the classical P−S and P−O bond cleavage. These results highlight the efficacy of AcMP11 to efficiently detoxify V‐series organophosphorus nerve agents and the necessity to ...
Valmir Baptista da Silva +5 more
wiley +1 more source

