Results 61 to 70 of about 687 (168)

Effects of low-level sarin and cyclosarin exposure on white matter integrity in Gulf War Veterans [PDF]

open access: yesNeuroToxicology, 2015
We previously found evidence of reduced gray and white matter volume in Gulf War (GW) veterans with predicted low-level exposure to sarin (GB) and cyclosarin (GF). Because loss of white matter tissue integrity has been linked to both gray and white matter atrophy, the current study sought to test the hypothesis that GW veterans with predicted GB/GF ...
Linda L, Chao   +2 more
openaire   +2 more sources

Green Computational Approach for Raman Spectroscopy Prediction: A Sustainable Method for Hazardous Chemical Database Construction

open access: yesChemistry–Methods, Volume 6, Issue 7, July 2026.
A green density functional theory‐based Raman prediction workflow is presented as a safe alternative to hazardous experimental characterization. The optimized computational model enables accurate spectral prediction, scalable database expansion, and structural differentiation using key P═O, C═N, and P–F Raman markers while minimizing waste and ...
Honghyun Kim   +3 more
wiley   +1 more source

Therapeutic Efficacy of Different Antidotal Mixtures Against Poisoning with GF-Agent in Mice

open access: yesActa Medica, 2004
The toxicity of cyclohexyl methylphosphonofluoridate (GF-agent; cyclosarin) and therapeutic efficacy of four oximes (trimedoxime, methoxime, obidoxime and HI-6) in combination with atropine or benactyzine (BNZ) was studied in mice.
Lucie Bartošová   +3 more
doaj   +1 more source

Micro/nanorobots for detecting and eliminating biological and chemical warfare agents

open access: yesBMEMat, Volume 4, Issue 1, March 2026.
Fuel‐powered and field‐driven micro/nanorobots provide a cutting‐edge platform to safeguard national security and defense. This review reports the latest research progress in micro/nanorobots in sensing and detoxifying biological and chemical warfare agents.
Song Li   +4 more
wiley   +1 more source

Toxicological analyses of the bone matrix: Successes and challenges

open access: yesArchaeometry, Volume 67, Issue 4, Page 1001-1021, August 2025.
Abstract This study aimed to conduct an in‐depth and systematic literature review dealing with toxicological analyses on human bone tissue and focusing on the forensic toxicological and archaeotoxicological field. Several studies have focused their research on medical drugs, drugs of abuse, and trace elements on both human cadavers and skeletal remains,
Gaia Giordano   +3 more
wiley   +1 more source

Substituted Monoquaternary Oximes as Reactivators of Cyclosarin- and Chlorpyrifos-Inhibited Acetylcholinesterase [PDF]

open access: yes, 2006
U ovome in vitro istraživanju testiran je reaktivacijski potencijal triju reaktivatora acetilkolinesteraze (AChE; EC 3.1.1.7) dobivenih iz monokvaternog reaktivatora pralidoksima.
Jun, Daniel   +3 more
core   +1 more source

A Thermostable Bacterial Metallohydrolase that Degrades Organophosphate Plasticizers

open access: yesChemBioChem, Volume 26, Issue 11, June 3, 2025.
This bacterial enzyme, cyclase‐phosphotriesterase (C‐PTE) from Ruegeria pomeroyi DSS‐3, shows significant potential for breaking down organophosphate pollutants. Beyond its capability to hydrolyze specific plasticizers such as triphenyl phosphate and tris(2‐chloropropyl) phosphate, C‐PTE's crystal structure reveals a binuclear zinc active site, and it ...
Dawei Ji   +5 more
wiley   +1 more source

Exploring the Physicochemical Properties of Oxime-Reactivation Therapeutics for Cyclosarin, Sarin, Tabun, and VX Inactivated Acetylcholinesterase

open access: yes, 2016
The inactivation of acetylcholinesterase (AChE) by organophosphorus agent (OP) compounds is a serious problem regardless of how the individual was exposed.
Jeffry D. Madura (1335309)   +3 more
core   +1 more source

Sulfonatocalix[4]arene‐Based Scavengers for V‐Type Nerve Agents with Enhanced Detoxification Activity

open access: yesChemistry – A European Journal, Volume 31, Issue 9, February 12, 2025.
Two is better than one. The introduction of a second hydroxamic acid substituents along the cavity of a sulfonatocalix[4]arene improves the activity with which this compound detoxifies highly toxic nerve agents of the V‐type to such an extent that its use as an antidote is now conceivable.
Patrick Gaß   +3 more
wiley   +1 more source

Detoxification of V‐Nerve Agents Assisted by a Microperoxidase: New Pathway Revealed by the Use of a Relevant VX Simulant

open access: yesChemBioChem, Volume 25, Issue 15, August 1, 2024.
The biocatalyzed oxidative detoxification of the V‐series simulant PhX with the microperoxidase AcMP11 affords the corresponding phosphonothioate as the prominent product instead of the classical P−S and P−O bond cleavage. These results highlight the efficacy of AcMP11 to efficiently detoxify V‐series organophosphorus nerve agents and the necessity to ...
Valmir Baptista da Silva   +5 more
wiley   +1 more source

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