Chromogenic and fluorogenic reagents for chemical warfare nerve agents' detection [PDF]
, 2007 The ease of production, the extreme toxicity of organophosphorus-containing nerve agents, and their facile use in terrorism attacks underscores the need to develop accurate systems to detect these chemicals.
Ana M. Costero +42 more
core +2 more sources
Eyeing up the Future of the Pupillary Light Reflex in Neurodiagnostics [PDF]
, 2018 This is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).The pupillary light reflex (PLR) describes the constriction and subsequent ...
Barbur +12 more
core +4 more sources
Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin [PDF]
Molecular Pharmacology, 2010 Organophosphorus (OP) nerve agents are potent toxins that inhibit cholinesterases and produce a rapid and lethal cholinergic crisis. Development of protein-based therapeutics is being pursued with the goal of preventing nerve agent toxicity and protecting against the long-term side effects of these agents.
Andrew C, Hemmert +9 more
openaire +2 more sources
Substrate Analogues for the Enzyme-Catalyzed Detoxification of the Organophosphate Nerve Agents-Sarin, Soman, and Cyclosarin. [PDF]
Biochemistry, 2021 The G-type nerve agents, sarin (GB), soman (GD), and cyclosarin (GF), are among the most toxic compounds known. Much progress has been made in evolving the enzyme phosphotriesterase (PTE) from Pseudomonas diminuta for the decontamination of the G-agents; however, the extreme toxicity of the G-agents makes the use of substrate analogues necessary ...
Bigley AN +3 more
europepmc +3 more sources
Colorimetric Detection of Warfare Gases by Polydiacetylenes Toward Equipment‐Free Detection [PDF]
, 2012 Rationally designed polydiacetylene (PDA) molecules have been developed for rapid, selective, sensitive, and convenient colorimetric detection of organophosphate (OP) nerve agents, a mass destruction weapon. Oxime (OX) functionality was incorporated into
Ahn +33 more
core +1 more source
Chemical warfare simulant-responsive polymer nanocomposites: Synthesis and evaluation [PDF]
, 2017 Nanomaterials that undergo a physical change upon chemical warfare agent (CWA) exposure can potentially be used in detectors to warn soldiers of their presence or in fabrics to provide on‐demand protection.
Herbert, Myles Benton +4 more
core +1 more source
Modified Biosensor for Cholinesterase Inhibitors with Guinea Green B as the Color Indicator
Biosensors, 2018 Colorimetric biosensors of cholinesterase inhibitors are ideal for fast, reliable, and very simple detection of agents in air, in water, and on surfaces.
Vladimír Pitschmann +5 more
doaj +1 more source
Imidazole aldoximes effective in assisting butyrylcholinesterase catalysis of organophosphate detoxification. [PDF]
, 2014 Intoxication by organophosphate (OP) nerve agents and pesticides should be addressed by efficient, quickly deployable countermeasures such as antidotes reactivating acetylcholinesterase or scavenging the parent OP.
Amitai, Gabriel +5 more
core
Systematic comparison of different techniques to measure hippocampal subfield volumes in ADNI2 [PDF]
, 2018 OBJECTIVE: Subfield-specific measurements provide superior information in the early stages of neurodegenerative diseases compared to global hippocampal measurements.
Alpert, K +11 more
core +3 more sources
Micro/nanorobots for detecting and eliminating biological and chemical warfare agents
BMEMat, Volume 4, Issue 1, March 2026.Fuel‐powered and field‐driven micro/nanorobots provide a cutting‐edge platform to safeguard national security and defense. This review reports the latest research progress in micro/nanorobots in sensing and detoxifying biological and chemical warfare agents.
Song Li +4 more
wiley +1 more source