Lipidation of a bioactive cyclotide-based CXCR4 antagonist greatly improves its pharmacokinetic profile in vivo. [PDF]
Chaudhuri D +7 more
europepmc +1 more source
The cyclotides: Novel macrocyclic peptides as scaffolds in drug design
Cyclotides are a novel class of circular, disulfide-rich peptides (similar to 30 amino acids) that display a broad range of bioactivities and have exceptionally high stability.
Simonsen, S., Daly, N. L., Craik, D. J.
core
Computational prediction of cyclotides from Viola odorata as potential inhibitors against the neuraminidase of Streptococcus pneumoniae. [PDF]
Sankar S +5 more
europepmc +1 more source
Resistance is futile: targeting multidrug-resistant bacteria with de novo Cys-rich cyclic polypeptides. [PDF]
Mourenza A, Ganesan R, Camarero JA.
europepmc +1 more source
Plant Peptides on the Rise: From Historical Insight to Future Applications. [PDF]
Wang S +5 more
europepmc +1 more source
Interaction of cyclotides and bacteria : A study of the cyclotide action and the bacterial reaction
The growing problem of antibiotic resistance and the lack of promising prospective antibiotics have forced us to search for new classes of antibiotics. Among the candidates to develop into future antibacterials are antimicrobial peptides (AMPs). These potent, broad spectrum compounds are important components of innate immunity of organism from all ...
openaire +1 more source
Peptides from plants and microorganisms: a defense strategy for biotic and abiotic stresses. [PDF]
Ha-Tran DM, Huang CC.
europepmc +1 more source
At the moment, there is growing concerned about the negative effects on human health, and the environment due to the widespread and indiscriminate use of conventional insecticides.
Ingrid María Cufre +5 more
doaj
Antimicrobial peptides: emerging next-generation strategy for sustainable plant disease management. [PDF]
Das D +6 more
europepmc +1 more source
Small and Versatile Cyclotides as Anti-infective Agents. [PDF]
Cândido ES +7 more
europepmc +1 more source

