Results 101 to 110 of about 1,652 (193)
Optimization of the cyclotide framework to improve cell penetration properties
Frontiers in Pharmacology, 2015 Cell penetrating peptides have been regarded as promising vectors to deliver hydrophilic molecules inside cells. Although they are great tools for research and have high potential as drug delivery systems, their application as drugs is impaired by their ...
Yen-Hua eHuang +4 more
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Cyclotides : a novel class of natural antibiotics
, 2011 Cyclotides are circular plant proteins that are approximately 30 amino acids long and have high heat and enzymatic stability. Their N- and C- termini are joined together to form a continuous cyclic conformation.
Ang, Koon Hwee
core
15N cyclotides by whole plant labeling
, 2008 Cyclotides are 28-37 amino acid peptides incorporating three disulfide bonds and a cyclic backbone. Their cyclic and knotted topology renders them immune to denaturation by heat or organic solvents and highly resistant to proteolysis.
Mylne, Joshua S., Craik, David J.
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Behavioral and physiological effects of Viola spp. cyclotides on Myzus persicae (Sulz.)
, 2020 Cyclotides are defense peptides produced by several plant families. Viola spp. (Violaceae) produce an array of cyclotides with varying biological activities.
Dancewicz, Katarzyna +5 more
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Synthesis and protein engineering applications of cyclotides
, 2017 Cyclotides are a group of plant-derived peptides with a head-to-tail cyclized backbone that is stabilized by three knotted disulfide bonds. Their exceptional stability and tolerance for residue substitutions have led to interest in their application as ...
Durek, Thomas +3 more
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The life cycle of cyclotides : biosynthesis and turnover in plant cells
, 2020 Key message Turnover rates have implications for understanding cyclotide biology and improving plant cell culture-based production systems. Cyclotides are a family of polypeptides recognized for a broad spectrum of bioactivities. The cyclic, cystine knot
Haugmo, Tobias, +7 more
core +1 more source
, 2006 Cyclotides are a large family of mini-proteins that have the distinguishing features of a head-to-tail cyclised backbone and a cystine knot formed by six conserved cysteine residues.
Cemazar, M., Craik, D. J.
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Molecular peptide grafting as a tool for creating new generation of biopeptides: A mini-review
Пищевые системыMolecular peptide grafting (MPG) is the isolation/synthesis of a bioactive fragment of a peptide/protein and its subsequent transfer to a target protein/peptide to create a new protein product with specified unique biological properties.
I. M. Chernukha +2 more
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Do Plant Cyclotides Have Potential As Immunosuppressant Peptides?
, 2016 Cyclotides are an abundant and diverse group of ribosomally synthesized plant peptides containing a cyclic cystine-knotted structure that confers them with remarkable stability. They are explored for their distribution in plants, although little is known
Christian W Gruber (2110414) +3 more
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Anti-HIV Cyclotides from the Chinese Medicinal Herb Viola yedoensis
, 2016 Cyclotides are macrocyclic plant peptides characterized by a knotted arrangement of three disulfide bonds. They display a range of interesting bioactivities, including anti-HIV and insecticidal activities.
Kirk R. Gustafson (131179) +5 more
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