Antimicrobial peptides (AMPs) are a class of short, usually positively charged, polypeptides which are widely used to overcome the threat of the antimicrobial resistance. The potential of the AMPs is increasing as a new class of antibiotics.
Asif Ali +10 more
doaj +1 more source
Cyclotides : a novel type of cytotoxic agents
Cytotoxic activities of three naturally occurring macrocyclic peptides (cyclotides) isolated from the two violets, Viola arvensis Murr. and Viola odorata L., were investigated.
Larsson, Rolf, +7 more
core
New Cyclotides Isolated from the Roots of Allexix batangae (Violaceae)
Cyclotides are a very abundant class of plant peptides that display signi?cant sequence variability around a conserved cystine-knot motif and a head-to-tail cyclized backbone conferring them with remarkable stability.
Ndogo Eteme, Olivier +4 more
core
Cyclotides : Tuning Parameters Toward Their Use in Drug Design
Cyclotides are plant proteins with a unique topology, defined as the cyclic cystine knot motif. The motif endows cyclotides with exceptional chemical and biological stability. They also exhibit a wide range of biological activities including insecticidal,
Yeshak, Mariamawit Yonathan
core
Discovery, Isolation, and Bactericidal Activity of a Cyclotide from <i>Spigelia anthelmia</i> L. (Loganiaceae). [PDF]
Akinleye TE +7 more
europepmc +1 more source
Exploring Immune Modulatory Effects of Cyclotide-Enriched Viola tricolor Preparations. [PDF]
Retzl B +5 more
europepmc +1 more source
The cyclotides are a family of naturally occurring peptides characterized by cyclic cystine knot (CCK) structural motif, which comprises a cyclic head-to-tail backbone featuring six conserved cysteine residues that form three disulfide bonds. This unique
Ulf, Göransson, +3 more
core
Tropical psychotria plants are a rich source for peptide inhibitors of human prolyl oligopeptidase. [PDF]
Hellinger R +6 more
europepmc +1 more source
A Systematic Review of Phytochemistry, Nutritional Composition, and Pharmacologic Application of Species of the Genus Viola in Noncommunicable Diseases (NCDs). [PDF]
Batiha GE +8 more
europepmc +1 more source
Effects of cyclotide-producing plants on the development and life history parameters of Leipothrix violarius. [PDF]
Pińkowska A +4 more
europepmc +1 more source

