Results 21 to 30 of about 2,702,703 (186)

Association of SNP rs.2414096 CYP19 gene with polycystic ovarian syndrome in Iranian women

International Journal of Reproductive BioMedicine, 2017
Background: Genetic factors are believed to play an important role in the etiology of polycystic ovarian syndrome (PCOS) which is the most common endocrinological disorder of women in their reproductive age.
Anahita Mehdizadeh, Seyed Mehdi Kalantar, Mohammad Hassan Sheikhha, Bibi Shahnaz Aali, Azam Ghanei   +4 more
doaj   +1 more source

Sex-Specific Gene Expression Ontogeny During Gonadal Development in Post-Metamorphic Xenopus tropicalis. [PDF]

Mol Reprod Dev
Post‐metamorphic gonadal development in Xenopus tropicalis was analyzed through integrated morphometric, histological, and transcriptional approaches. Males showed upregulation of cyp17, amh, and amhr2, whereas females exhibited an increased aldh1a2 and ddx4.
Marini D, Roza M, Berg C, Brouard V.
europepmc   +2 more sources

Aromatase (CYP19) gene variants influence ovarian response to standard gonadotrophin stimulation. [PDF]

J Assist Reprod Genet, 2012
PURPOSE: The association of cytochrome P450 aromatase gene CYP19(TTTA) ( n ) polymorphism with ovarian response to FSH stimulation was explored. METHODS: Three hundred women undergoing medically assisted reproduction and 300 women with at least one ...
Lazaros LA, Hatzi EG, Xita NV, Makrydimas GV, Kaponis AI, Takenaka A, Kosmas IP, Sofikitis NV, Stefos TI, Zikopoulos KA, Georgiou IA.   +10 more
europepmc   +2 more sources

The association of aromatase (CYP19) gene variants with sperm concentration and motility. [PDF]

Asian J Androl, 2011
The irreversible transformation of androgens into oestrogens is catalysed by cytochrome P450 aromatase. In the present study, we explored the contribution of the (TTTA)(n) polymorphism in the aromatase gene (CYP19) to sperm concentration and motility. Ninety normozoospermic and 60 oligospermic men were examined during infertility examinations.
Lazaros L, Xita N, Kaponis A, Hatzi E, Plachouras N, Sofikitis N, Zikopoulos K, Georgiou I.   +7 more
europepmc   +4 more sources

Unveiling the Role of Vitamin D/VDR in Promoting Endometrial Decidualization. [PDF]

Int J Endocrinol
Vitamin D’s impact on reproductive health, particularly endometrial receptivity, has attracted significant attention. This study investigated the effects of vitamin D and its receptor (VDR) on decidualization in human endometrial stromal cells (HESCs). An in vitro decidualization model was established by culturing immortalized T‐HESC or primary HESC in
Guo J, Tian X, Liu H, Lu Q, Cao G.
europepmc   +2 more sources

Orexin Decreases Aromatase Gene Expression in The Hypothalamus of Androgenized Female Rats [PDF]

International Journal of Fertility and Sterility, 2016
Background Orexin is a hypothalamic orexigenic neuropeptide, which third cerebral injection of it mainly exerts inhibitory effects on reproductive functions.
Maliheh Salimi, Zahra Alishah, Homayoun Khazali, Fariba Mahmoudi   +3 more
doaj   +1 more source

Association of CYP19 and ESR1 Pleiotropic Genes With Human Longevity [PDF]

The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2010
Aromatase (CYP19) and estrogen receptor-alpha (ESR1) are involved in the metabolism of estrogens, which have a relevant role in female and male aging. Moreover, due to their influence on fertility, both genes may be part of the longevity-fertility trade-off mechanism.
CORBO, Rosa Maria, ULIZZI, Laura, L. Positano, R. Scacchi   +3 more
openaire   +7 more sources

Molecular characterization and association studies of CYP19 (aromatase) allelic variants with reproduction and production traits in Sahiwal and Hariana cattle

Indian Journal of Animal Sciences, 2022
Anestrus is a major reproductive problem in bovines which occurs due to less secretion of estrogen from the ovarian follicles. Enzyme cytochrome P450 aromatase which helps in estrogen biosynthesis is encoded by CYP19 gene.
VISHAKHA UTTAM, MADHU TIWARI, SATYENDRA PAL SINGH, DEEPAK SHARMA, AVNEESH KUMAR, ADITYA KUMAR   +5 more
doaj   +1 more source

Cytochrome P450 aromatase gene (CYP19) expression in gastric cancer [PDF]

Gastric Cancer, 2008
The secretion of biologically active estrogen through the conversion of circulating precursor androgens has been suggested to play important roles in the pathophysiology of estrogen-dependent carcinomas. In the present study, we examined aromatase expression in gastric carcinoma.Nineteen specimens of gastric carcinoma were obtained from Japanese ...
Masao, Izawa, Masashi, Inoue, Mitsuhiko, Osaki, Hisao, Ito, Tasuku, Harada, Naoki, Terakawa, Masahide, Ikeguchi   +6 more
openaire   +2 more sources

Single Nucleotide Polymorphisms in the Promoter of CYP19 Gene in Cattle Bred in Iraq

Maǧallaẗ al-baṣraẗ al-ʻulūm al-zirāʻiyyaẗ, 2020
The present study was undertaken to characterize the genetic diversity of the aromatase cytochrome P450 (CYP19) gene in 34 cows (15 local, 14 Holstein, and 5 Crosses) in Iraq. The objectives of the present study are to detect SNPs (mutations) in promoter
Salah H. Faraj, Asaad Y. Ayied, Khalaf A. H. Al-Rishdy   +2 more
doaj   +1 more source