Results 51 to 60 of about 2,702,703 (186)

Screening of a panel of steroid-related genes showed polymorphisms of aromatase genes confer susceptibility to advanced stage endometriosis in the Taiwanese Han population

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2013
Objective: To establish a multilocus model for studying the effect of steroid-related genes on advanced stage endometriosis. Materials and methods: A total of 121 patients with advanced stage endometriosis and 171 control women were included.
Cheng-Hsuan Wu   +4 more
doaj   +1 more source

Sex hormones genes expression and sexual dysfunction association among male heroin addicts at Zagazig University Hospitals, Egypt [PDF]

open access: yesZagazig Journal of Forensic Medicine and Toxicology, 2018
Objectives: Drug addiction becomes one of the grave problems worldwide, which has much health adverse effects. There are many reports relating Sexual dysfunction to heroin addiction that also affecting sex hormones.
Reem Allam   +4 more
doaj   +1 more source

Cyp19 expression and sex change timing in captive-bred false clownfish

open access: yesBrazilian Journal of Biology, 2023
The false clown anemonefish (Amphiprion ocellaris) is a protandrous hermaphrodite with a distinctive reproductive behavior. This study elucidates the genetic mechanisms and timing of sex changes in captive-bred A. ocellaris by examining the expression of
J. Thamnawasolos, C. Boonphakdee
doaj   +1 more source

Cocrystallization and Micronization as Strategies to Optimize the Bioavailability of Naringin and Naringenin Molecules: A Comprehensive Review of In Vivo and In Vitro Pharmaceutical Applications

open access: yesCrystal Research and Technology, Volume 61, Issue 7, July 2026.
Naringin and naringenin exhibit well‐recognized therapeutic potential; however, they face limitations related to solubility and bioavailability. Micronization increases surface area and enhances absorption. Notably, cocrystallization stands out as a primary strategy for particle optimization, as it refines physicochemical properties, improves ...
Emilia Rodrigues Almeida   +4 more
wiley   +1 more source

Update of the risk assessment on emerging and novel brominated flame retardants in food

open access: yesEFSA Journal, Volume 24, Issue 7, July 2026.
Abstract The European Commission asked EFSA to update its 2012 risk assessment on Emerging and Novel brominated flame retardants (BFRs) in food. Since the previous Opinion, further information was collected for a total of 27 BFRs. The CONTAM Panel concluded that TDBPP, DBPNG and TBNPA are considered genotoxic and carcinogenic.
EFSA Panel on Contaminants in the Food Chain (CONTAM)   +33 more
wiley   +1 more source

Placental biomarkers of phthalate effects on mRNA transcription: application in epidemiologic research

open access: yesEnvironmental Health, 2009
Background CYP19 and PPARγ are two genes expressed in the placental trophoblast that are important to placental function and are disrupted by phthalate exposure in other cell types.
Nelson Heather   +7 more
doaj   +1 more source

The Alternative Noncoding Exons 1 of Aromatase (Cyp19) Gene Modulate Gene Expression in a Posttranscriptional Manner [PDF]

open access: yesEndocrinology, 2009
Aromatase (Cyp19) is a key enzyme in estrogen biosynthesis and an important target in endocrine therapy for estrogen receptor (ER)-positive postmenopausal breast cancer. Aromatase transcription is driven by multiple tissue-specific promoters, which result in the production of various mRNA transcripts that contain an alternative noncoding exon 1 ...
Hanzhou, Wang, Rong, Li, Yanfen, Hu
openaire   +2 more sources

Cytochrome P450 aromatase (CYP19) gene expression in ovarian granulose cells of hypothyroid rats induced by propylthiouracil

open access: yes, 2014
Thyroid hormones are proven to have a direct effect on granulose cells, luteal cells and oocytesdue to their role in gonadotropin action on steroid hormone production.
Soejono, Sri Kadarsih   +2 more
core   +1 more source

TGF-β1 regulation of estrogen production in mature rat Leydig cells. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Besides androgens, estrogens produced in Leydig cells are also crucial for mammalian germ cell differentiation. Transforming growth factor-β1 (TGF-β1) is now known to have multiple effects on regulation of Leydig cell function.
Man-Li Liu   +8 more
doaj   +1 more source

2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside improves female ovarian aging

open access: yesFrontiers in Cell and Developmental Biology, 2022
Reduced fertility associated with normal aging may reflect the over-maturity of oocytes. It is increasingly important to reduce aging-induced infertility since recent trends show people marrying at later ages.
Hung-Yun Lin   +27 more
doaj   +1 more source

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