HSP90 inhibition potentiates oxidant-based antimelanoma action of novel thioquercetin derivatives by compromising AhR/CYP1A1 pathway. [PDF]
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Systematic evaluation of genetic polymorphisms in carcinogen metabolizing enzymes associated with oral potentially malignant disorders progression to oral cancer risk. [PDF]
Xu Z, Zhu Y, Shi L, Liu W.
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Is Exposure to Certain Endocrine-Disrupting Chemicals Associated with Increased Skin Cancer Risk? [PDF]
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Cobinamide, a Vitamin B<sub>12</sub> Analog, Attenuates Benzo[a]pyrene and Pyrene Toxicity Through Selective Redox Modulation. [PDF]
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IBD risk locus rs1077773 enhances aryl hydrocarbon receptor activity and modulates immune cell function in vitro. [PDF]
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Dietary tryptophan ameliorates metalaxyl-induced colitis by restoring microbial tryptophan metabolism and aryl hydrocarbon receptor activation. [PDF]
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Cytochrome P-450 CYP1A1 is involved in the metabolism of polycyclic aromatic hydrocarbons (PAHs) that are derived from meat intake and tobacco smoking. Expression of the CYP1A1 gene is induced by compounds present in cruciferous vegetables.
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