Results 101 to 110 of about 27,792 (251)
Evaluation of CYP2C19 Genetic Variant and Its Lack of Association with Valproic Acid Plasma Concentrations Among Zhuang and Han Schizophrenia Patients in Guangxi [PDF]
Jun Mei Teng,1 Shuiqing Qin,2 Danyu Lu,1 Yefa Gu,3 Shi Jie Tang,3 Qiong Yan,1 Jiawei Yao,1 Chao Zhang1 1Laboratory Department, The Fifth People’s Hospital of Nanning, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China; 2Department of ...
Yao J +7 more
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พารามิเตอร์ทางเภสัชจลนศาสตร์ของวอริโคนาโซลแบ่งตามฟีโนไทป์ของ CYP2C19 Voriconazole Pharmacokinetic Parameters Based on CYP2C19 Phenotype [PDF]
, 2019 บทคัดย่อ วัตถุประสงค์: เพื่อหาค่าพารามิเตอร์ทางเภสัชจลนศาสตร์ของวอริโคนาโซลซึ่งจะนำไปสู่ขนาดวอริโคนาโซลที่เหมาะสมโดยแบ่งตามฟีโนไทป์ของ CYP2C19 เพื่อให้ได้ระดับยาต่ำสุดในเลือดอยู่ในช่วงการรักษาที่ 1-5 มก./ลิตร วิธีการศึกษา: การวิจัยเชิงสำรวจโดยการเก็บข ...
Prawat Chantharit, ประวัฒน์ จันทฤทธิ์ +3 more
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Melatonin Levels in 89 Individuals With Smith Magenis Syndrome
American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2260-2272, October 2026.ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley +1 more source
, 2017 Karin B Mirzaev,1 Elena M Zelenskaya,2 Olga L Barbarash,3 Vladimir I Ganyukov,3 Konstantin A Apartsin,4,5 Natalya O Saraeva,4 Konstantin Y Nikolaev,6,7 Kristina A Ryzhikova,1 Galina I Lifshits,2,5,7 Dmitry A Sychev1 1Russian Medical Academy of Continuous
Zelenskaya EM +9 more
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Escitalopram Personalized Dosing: A Population Pharmacokinetics Repository Method
Drug Design, Development and Therapy, 2023 Xin Liu,1– 3 Gehang Ju,1– 3 Wenyu Yang,4 Lulu Chen,3,5,6 Nuo Xu,4 Qingfeng He,4 Xiao Zhu,4,* Dongsheng Ouyang1– 3,5,* 1Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, People’s Republic of China ...
Liu X +7 more
doaj
Narrative Review: Polimorfisme CYP2C19 dan Pengaruhnya terhadap Metabolisme Klopidogrel [PDF]
, 2021 Latar Belakang: Obat dengan jenis dan dosis yang sama dapat menghasilkan respons yang berbeda pada setiap individu. Perbedaan dalam respons obat tersebut sangat dipengaruhi oleh variabilitas dalam jalur farmakokinetik dan farmakodinamik.
SAPUTRI, Mei Dhea
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Association between CYP2C19 gene polymorphisms and Helicobacter pylori infection in Hainan region
BMC Infectious DiseasesObjective This study was to investigate CYP2C19 gene and their association with H. pylori infection in the region of Hainan. Methods We conducted CYP2C19 genotype analysis in Hainan.
Shimei Huang +8 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 914-929, October 2026.Precision medicine offers the opportunity to improve the benefit–risk profile of new therapies by prospectively identifying patients most likely to respond or least likely to experience harm; however, its systematic integration into drug development remains inconsistent outside oncology.
Ingrid Holst‐Laubjerg +1 more
wiley +1 more source
Exploring the Potential Role of CYP2C19 Genetic Variability in Cenobamate Treatment
Applied SciencesBackground: Cenobamate is a novel antiseizure medication with potential interactions involving cytochrome P450 enzymes, including CYP2C19. Genetic variability in CYP2C19 may influence drug metabolism and tolerability, although its clinical relevance in ...
Giovanni Falcicchio +8 more
doaj +1 more source
Common CYP2C19 Alleles in Gaza Strip Population [PDF]
, 2006 CYP is a heme-containing enzyme present in liver, widely distributed from bacteria to mammals, and comprises a superfamily of metabolic enzymes that play an important role in the metabolism of endogenous substrates, environmental toxins, carcinogenic ...
Gharbieh, Amany Musa
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