Results 91 to 100 of about 48,854 (243)

Pharmacogenetics of Anesthetic and Analgesic Agents: CYP2D6 Genetic Variations [PDF]

, 2005
Ulrike M. Stamer, Frank Stüber
openalex   +1 more source

Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer

, 2015
Tamoxifen is the standard-of-care treatment for estrogen receptor-positive premenopausal breast cancer. We examined tamoxifen metabolism via blood metabolite concentrations and germline variations of CYP3A5, CYP2C9, CYP2C19 and CYP2D6 in 587 ...
A Ahmad, A Gaedigk, A Tfayli, B Chowbay, B Eccles, B Ganchev, B Makubate, C Davies, C McCowan, D Eccles, D Eccles, DL Hershman, DL Hershman, E Copson, E Schaeffeler, Early Breast Cancer Trialists’ Collaborative Group, EJA Bowles, EP Winer, H Brauch, H Brauch, H Brauch, H Brauch, I Zineh, J S L Lim, J Sistonen, JE Abraham, JK Coller, JM Rae, JM Rae, JSL Lim, K Dickschen, K Kiyotani, K Kiyotani, K Kiyotani, KJ Ruddy, L Madlensky, M Dowsett, M Eichelbaum, M Gnant, M Schwab, M Z Habbal, MA Province, MD Johnson, MF Barginear, MJ Ratain, MM Regan, MM Regan, MP Goetz, N K Zgheib, N S Wong, O Pagani, P Saladores, PH Saladores, PM Ravdin, PY Maximov, R C H Ng, R Dent, R McCague, Richard G. Gray, RR Love, RT Chlebowski, S Gerty, S Winter, T Mürdter, TE Mürdter, TL Lash, UM Zanger, UM Zanger, VC Jordan, VO Dezentjé, W Lorizio, W Schroth, W Schroth, W Schroth, WJ Irvin Jr, WJ Lu, Y Jin, Y S Yap, YC Lim, Z Awada, Z Desta   +80 more
core   +1 more source

Influence of 5-HT_3bReceptor AAG Deletion Mutation and CYP2D6*10 on the Ondansetron Treatment [PDF]

, 2006
Ju‐Hee Kang, Helen Ki Shinn, Sung-Ho Shin, Chang Shin Park, Hong Sik Lee, Jang Ho Song, Young Deog, Hae Jin Park   +7 more
openalex   +1 more source

Enriching Medication Review with a Pharmacogenetic Profile – A Case of Tamoxifen Adverse Drug Reactions

Pharmacogenomics and Personalized Medicine, 2021
Chiara Jeiziner,1 Céline K Stäuble,1,2 Markus L Lampert,1 Kurt E Hersberger,1 Henriette E Meyer zu Schwabedissen2 1Pharmaceutical Care Research Group, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland ...
Jeiziner C, Stäuble CK, Lampert ML, Hersberger KE, Meyer zu Schwabedissen HE   +4 more
doaj  

Real time PCR detection of common CYP2D6 genetic variants and its application in a Karen population study

Malaria Journal, 2018
Background Plasmodium vivax malaria is characterized by relapses arising from the hypnozoite stages in the liver. The only currently registered drug for radical treatment to prevent relapse is primaquine.
Kanokpich Puaprasert, Cindy Chu, Naowarat Saralamba, Nicholas P. J. Day, Francois Nosten, Nicholas J. White, Arjen M. Dondorp, Mallika Imwong   +7 more
doaj   +1 more source

The CYP2D6 VCF Translator [PDF]

The Pharmacogenomics Journal, 2016
W, Qiao, J, Wang, B S, Pullman, R, Chen, Y, Yang, S A, Scott   +5 more
openaire   +2 more sources

CYP2D6*2N Allele

, 2020
National Cancer Institute
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Solanidine is a sensitive and specific dietary biomarker for CYP2D6 activity

Human Genomics
Background Individual assessment of CYP enzyme activities can be challenging. Recently, the potato alkaloid solanidine was suggested as a biomarker for CYP2D6 activity.
Johanna I. Kiiski, Mikko Neuvonen, Mika Kurkela, Päivi Hirvensalo, Kreetta Hämäläinen, E. Katriina Tarkiainen, Johanna Sistonen, Mari Korhonen, Sofia Khan, Arto Orpana, Anne M. Filppula, Marko Lehtonen, Mikko Niemi   +12 more
doaj   +1 more source

Variantes alélicas de CYP2D6: *4, *6 y *10 en una muestra de residentes del estado Aragua, Venezuela

Revista Peruana de Medicina Experimental y Salud Pública
El objetivo del estudio fue determinar la frecuencia de las variantes del gen CYP2D6: *4, *6 y *10 y predecir el fenotipo metabolizador en una muestra de 145 individuos no consanguíneos, aparentemente sanos, residentes del estado Aragua, Venezuela.
Carlos Flores-Angulo, Cecilia Villegas, Yuselin Mora, José Antonio Martínez, Teresa Oropeza, Nancy Moreno   +5 more
doaj   +2 more sources

The influence of CYP2D6 genotype on trough plasma perhexiline and cis‐OH‐perhexiline concentrations following a standard loading regimen in patients with myocardial ischaemia [PDF]

, 2005
Benjamin J. Davies, Janet K. Coller, Heather M. James, Andrew A. Somogyi, John D. Horowitz, Benedetta C. Sallustio   +5 more
openalex   +1 more source