Results 71 to 80 of about 1,046 (126)
Mycoses, Volume 68, Issue 11, November 2025.ABSTRACT Objectives This study reports the first isolation of a multidrug‐resistant Trichophyton rubrum strain in China, characterizing its drug resistance profile and mechanisms. Methods The isolate was identified by internal transcribed spacer (ITS) sequencing and phylogenetic analysis.
Ge Song +8 more
wiley +1 more source
Primers used to amplify the six validated genes as well as cyp51A (positive control).
, 2012 Primers used to amplify the six validated genes as well as cyp51A (positive control).
Bas E. Dutilh (118607) +7 more
core +1 more source
Azole-resistant aspergillus fumigatus containing a 34-bp tandem repeat in cyp51A promoter is isolated from the environment in Japan [PDF]
application/pdfAzole-resistant strains of Aspergillus fumigatus containing a tandem repeat in the cyp51A promoter and amino acid substitution(s) have been isolated in the environment worldwide; however, this type of resistant strain had never been ...
Onishi, Kenji +6 more
core +2 more sources
In Vitro Activity of Nitroxoline (5‐Nitro‐8‐Hydroxyquinoline) Against Aspergillus Species
Mycoses, Volume 68, Issue 11, November 2025.ABSTRACT Background Nitroxoline is an old antibiotic currently approved for the treatment of uncomplicated urinary tract infections. Its mode of action is based on the chelation of bivalent cations, such as zinc. Objectives As zinc plays a central role in the metabolism of Aspergillus spp., we performed antifungal susceptibility testing against ...
Ada Hoffmann +7 more
wiley +1 more source
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
Advanced Science, Volume 12, Issue 37, October 6, 2025.The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda +12 more
wiley +1 more source
Regulation of Ergosterol Biosynthesis in Pathogenic Fungi: Opportunities for Therapeutic Development
MicroorganismsErgosterol plays a dual role in fungal pathogenesis and azole resistance, driving key advancements in the understanding of its biosynthesis regulation.
Lingyun Song +6 more
doaj +1 more source
Mycoses, Volume 68, Issue 8, August 2025.ABSTRACT Background Until 2020, azole resistance in Aspergillus fumigatus complex isolates in New Zealand was due to cyp51A hot spot mutations. This report details the appearance of environment‐linked tandem repeat (TR)‐related azole resistance genotypes since 2021. Methods Isolates were tested by broth micro‐dilution.
Arthur J. Morris +5 more
wiley +1 more source
Intragenic cyp51A recombination in A. fumigatus ascospore progeny.
, 2023 (A) Whole contents of single cleistothecia plated on Malt Extract Agar plates. (B) Whole contents of a single cleistothecium selected for cyp51A recombinants by plating instead on MEA + 10 μg/mL itraconazole.
Joost van den Heuvel (844702) +10 more
core +1 more source
Identification of Fungal Species and Detection of Azole-Resistance Mutations in the Aspergillus fumigatus cyp51A Gene at a South Korean Hospital [PDF]
, 2020 Purpose: With changing fungal epidemiology and azole resistance in Aspergillus species, identifying fungal species and susceptibility patterns is crucial to the management of aspergillosis and mucormycosis.
김정호 +13 more
core +1 more source
mBioAzoles are the primary antifungal drugs used to treat infections caused by Aspergillus fumigatus. However, the emergence of azole resistance in A. fumigatus has become a global health concern despite the low proportion of resistant isolates in natural ...
Shu Chen +8 more
doaj +1 more source