Exogenous H2S Regulates the Expression of Cystathionine Gamma-Lyase in HUVECs During Hypoxia
Cystathionine gamma-lyase (CSE) is an essential Hydrogen sulphide (H2S)-producing enzyme that regulates diverse processes related to cardiovascular function. It is crucial to understand how exogenous H2S regulates CSE expression in vascular endothelial cells during hypoxia.
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Sodium aescinate-induced hepatotoxicity via ATF4/GSH/GPX4 axis-mediated ferroptosis
Sodium aescinate (SA), a natural plant extract with various bioactivities, is widely used to treat oedema and inflammation in clinics. However, adverse events, including liver injury, kidney injury, and phlebitis, have been reported in patients with SA ...
Chen Xi +4 more
doaj +1 more source
Regulation of cystathionine gamma-lyase/H₂S system and its pathological implication.
Hydrogen sulfide (H2S) is a highly diffusible gasotransmitter, that influence cellular and organ functions by a number of different mechanisms. Cystathionine gamma-lyase (CSE) is one major H2S-producing enzyme with L-cysteine as the main substrate in mammalian cells.
Kexin, Zhao +3 more
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Bioenergetic effects of hydrogen sulfide suppress soluble Flt-1 and soluble endoglin in cystathionine gamma-lyase compromised endothelial cells. [PDF]
Sanchez-Aranguren LC +6 more
europepmc +1 more source
Cystathionine gamma-lyase-mediated hypoxia inducible factor 1-alpha expression drives clear cell ovarian cancer progression. [PDF]
El-Naggar AM +27 more
europepmc +1 more source
The Dysregulation of microRNA-30b Directly Regulates Cystathionine Gamma-Lyase and Exhibits Poor Invasion Activity in Preeclampsia. [PDF]
Saxena S, John BA, Verma N, Mishra M.
europepmc +1 more source
Retraction notice to "Bioinformatic analyzes and validation of cystathionine gamma-lyase as a prognostic biomarker and related to immune infiltrates in hepatocellular carcinoma" [Heliyon 9 (2023) e16152]. [PDF]
Xiang J +9 more
europepmc +1 more source
The expression of cystathionine gamma-lyase is regulated by estrogen receptor alpha in human osteoblasts. [PDF]
Lambertini E +8 more
europepmc +1 more source
Cystathionine-Gamma-Lyase-Derived Hydrogen Sulfide-Regulated Substance P Modulates Liver Sieve Fenestrations in Caecal Ligation and Puncture-Induced Sepsis. [PDF]
Gaddam RR +6 more
europepmc +1 more source
CYSTATHIONINE gamma-LYASE IS AN ENDOGENOUS MODULATOR OF OXIDATIVE STRESS
Bos, Eelke M. +4 more
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