Results 111 to 120 of about 3,506 (234)
Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Aims Acute kidney injury (AKI) affects up to one‐third of neonates admitted to neonatal intensive care units (NICUs). NICUs are highly data‐rich environments, offering opportunities to develop clinical prediction rules (CPRs) that use clinical and demographic data to estimate AKI risk.
Dermot Wildes +7 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Sugar crops, including but not limited to sugarcane, sugar beet, sweet sorghum and stevia, are major sources of sugar production in the world. However, conventional breeding approaches, limited by long breeding cycles, low efficiency and restricted capacity to improve complex traits in sugar crops, are increasingly insufficient to address the ...
Peilin Wang +7 more
wiley +1 more source
Cystatins, cysteine peptidase inhibitors, as regulators of immune cell cytotoxicity
, 2016 Cystatins comprise a superfamily of evolutionarily related proteins, present in all living organisms, from protozoa to mammals. They act as inhibitors of cysteine peptidases although they can also function independently of their inhibitory function ...
Mateja Prunk +7 more
core +1 more source
BETA2-STRAND OF SALIVARY CYSTATINS: A "CHEMELEON SEQUENCE"
, 2009 Secondary structure prediction of salivary cystatins S, SA, and SN carried out by several methods label the 39–58 sequence (b2-strand) as predominantly a-helical.
PETRUZZELLI, Raffaele +3 more
core
Experimental Physiology, EarlyView.Abstract Left ventricular assist devices have gained traction both as a bridge therapy and as a destination therapy in the management of heart failure. Many of these devices reinstate blood flow in a continuous manner as opposed to the pulsatile flow present in normal physiology.
Tania Warnakulasuriya +2 more
wiley +1 more source
Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.ABSTRACT Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a fatal neurodegenerative disease primarily affecting motor neurons. Two key protein inclusions found in lower motor neurons serve as neuropathological hallmarks of the disease in human tissue: the TDP43‐positive inclusion and the cystatin C‐positive Bunina body.
Sarah M. Granger +5 more
wiley +1 more source
The cystatins: Protein inhibitors of cysteine proteinases
, 1991 The last decade has witnessed enormous progress of protein inhibitors of cysteine proteinases concerning their structures, functions and evolutionary relationships.
Bode, Wolfram +3 more
core +1 more source
Natural History of Chronic Kidney Disease in Sickle Cell Disease
American Journal of Hematology, Volume 101, Issue 7, Page 1456-1477, July 2026.ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2028-2048, July 2026.This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst +8 more
wiley +1 more source