Results 11 to 20 of about 116 (116)
Journal of Health Care for the Poor and Underserved, 2010 Cystatins, the classical inhibitors of C1 cysteine proteinases, have been extensively studied and reviewed in the literature. Over the last 20 years, however, proteins containing cystatin domains but lacking protease inhibitory activities have been identified, and most likely more will be described in the near future.
Josiah, Ochieng, Gautam, Chaudhuri
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Cystatins in Immune System [PDF]
Journal of Cancer, 2013 Cystatins comprise a large superfamily of related proteins with diverse biological activities. They were initially characterised as inhibitors of lysosomal cysteine proteases, however, in recent years some alternative functions for cystatins have been proposed.
Špela Magister, Janko Kos
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Cystatins in Health and Diseases [PDF]
International Journal of Peptide Research and Therapeutics, 2008 The Cystatins constitute a large group of evolutionary related proteins with diverse biological activities. They have been recently realized as instrumental in myriad of pathophysiological conditions. They have been implicated in various pathological conditions.
Aaliya Shah, Bilqees Bano
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Cysteine proteinases and cystatins [PDF]
Brazilian Archives of Biology and Technology, 2003 This review describeds the definition, localization, functions and examples of cysteine proteinases and their protein inhibitors in vertebrate, non-vertebrate animals and plants. These inhibitors are related with defense mechanisms of plant against pests.
Oliveira, Adeliana S. +2 more
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Cystatin C: A Primer for Pharmacists [PDF]
Pharmacy, 2020 Pharmacists are at the forefront of dosing and monitoring medications eliminated by or toxic to the kidney. To evaluate the effectiveness and safety of these medications, accurate measurement of kidney function is paramount. The mainstay of kidney assessment for drug dosing and monitoring is serum creatinine (SCr)-based estimation equations.
Hilary R. Teaford +4 more
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Cystatine C et risque cardiovasculaire [PDF]
Annales de biologie clinique, 2009 Abstract Background: Patients with chronic kidney disease (CKD) are at high risk for developing cardiovascular disease (CVD) and cardiovascular events. Cystatin C, a protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect ...
TAGLIERI, NEVIO, Koenig W, Kaski C.
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Cystatin 11: A New Member of the Cystatin Type 2 Family [PDF]
Endocrinology, 2002 Cystatin (CST)11, a novel member of the CST type 2 family of cysteine protease inhibitors, was identified in Macaca mulatta epididymis by subtractive hybridization cloning. The human CST11 gene on chromosome 20p11.2 is located near three other CST genes expressed predominantly in the male reproductive tract.
Susan H. Hall +11 more
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Helminth-derived cystatins: the immunomodulatory properties of an Ascaris lumbricoides cystatin
Parasitology, 2021 AbstractHelminth infections such as ascariasis elicit a type 2 immune response resembling that involved in allergic inflammation, but differing to allergy, they are also accompanied with strong immunomodulation. This has stimulated an increasing number of investigations, not only to better understand the mechanisms of allergy and helminth immunity but ...
Luis Caraballo +2 more
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Hepatology, EarlyView., 2022 Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino +14 more
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BioMolecular Concepts, 2011 AbstractCystatins are small proteins, typically composed of 100–120 amino acids, which together with similar proteins devoid of inhibitory properties, belong to a cystatin ‘superfamily’. Cystatins can do more than just inhibit proteases: two important aspects described here are aggregation properties linked to misfolding diseases and the unique ability
Veronica Esposito, Piero Andrea Temussi
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