Results 41 to 50 of about 3,702 (189)
Frontiers in Bioscience, 2009 Cystatins are natural cysteine protease inhibitors which belong to a superfamily of proteins with wide occurrence in tissues. The cystatins have been shown to play multiple roles in normal and disease processes. In many different cancers the cathepsins, enzymes inhibited by cystatins, are elevated and participate in tumor growth and invasion.
openaire +2 more sources
Cystatins: unravelling the biological implications for neuroprotection
Archives of Medical Science, 2023 Cystatins, a family of proteins known for their inhibitory role against cysteine proteases, have garnered significant attention in the field of neurodegeneration. Numerous genetic, experimental, and clinical studies concerning cystatin C suggest it plays
Bartłomiej Stańczykiewicz +3 more
doaj +1 more source
Tick salivary protein Cystatin: structure, anti-inflammation and molecular mechanism
Ticks and Tick-Borne DiseasesTicks are blood-sucking ectoparasites that secrete immunomodulatory substances in saliva to hosts during engorging. Cystatins, a tick salivary protein and natural inhibitor of Cathepsins, are attracting growing interest globally because of the ...
Xin Gao +9 more
doaj +1 more source
Salivary cystatins - biological role and diagnostical value [PDF]
, 2014 Introduction: This paper provides insights of the latest studies regarding the structure, properties and taction of cystatins belonging to family II, salivary cystatins in particular. Materials and methods: Relevant articles on the topic for the period
Ferdohleb, Eugenia
core +1 more source
Folia Histochemica et Cytobiologica, 2012 A Surface Plasmon Resonance Imaging (SPRI) sensor based on bromelain or chymopapain or ficin has been developed for specific cystatin determination.
Anna Sankiewicz +2 more
doaj +1 more source
TcCYPR04, a Cacao Papain-Like Cysteine-Protease Detected in Senescent and Necrotic Tissues Interacts with a Cystatin TcCYS4. [PDF]
PLoS ONE, 2015 The interaction amongst papain-like cysteine-proteases (PLCP) and their substrates and inhibitors, such as cystatins, can be perceived as part of the molecular battlefield in plant-pathogen interaction.
Thyago Hermylly Santana Cardoso +9 more
doaj +1 more source
MicroorganismsDespite continuous and extensive global efforts in the fight against tuberculosis (TB), this infectious disease continues to exert a tremendous burden on public health concerns and deaths worldwide.
Manoj Mandal +3 more
doaj +1 more source
Folia Histochemica et Cytobiologica, 2012 The activity of cysteine peptidases (cathepsins B and L) was estimated in homogenates of tissues sampled during surgery from 60 patients operated due to colorectal tumors.
Julia Rudno-Rudzinska +7 more
doaj +1 more source
Cystatin C and Uncontrolled Hypertension
The Anatolian Journal of Cardiology, 2020 Increased serum level of cystatin C, a sensitive biomarker for renal function, seems to predict adverse cardiovascular events. We investigated the predictive value of serum cystatin C for controlling hypertension in an observational study.We screened 1037 adults residing in both rural and urban communities.
Omaygenç, Mehmet Onur +3 more
openaire +5 more sources
Tick sialostatins L and L2 differentially influence dendritic cell responses to Borrelia spirochetes
Parasites & Vectors, 2015 Background Transmission of pathogens by ticks is greatly supported by tick saliva released during feeding. Dendritic cells (DC) act as immunological sentinels and interconnect the innate and adaptive immune system. They control polarization of the immune
Jaroslava Lieskovská +6 more
doaj +1 more source