Results 61 to 70 of about 5,771 (244)

Octreotide may improve pharyngocutaneous fistula healing through downregulation of cystatins: A pilot study

open access: yesLaryngoscope Investigative Otolaryngology, 2023
Background Pharyngocutaneous fistula (PCF) and salivary leaks are well known complications of head and neck surgery. The medical management of PCF has included the use of octreotide without a well‐defined understanding of its therapeutic mechanism.
Jonathan Cohen   +7 more
doaj   +1 more source

Exploring the mialome of ticks: An annotated catalogue of midgut transcripts from the hard tick, Dermacentor variabilis (Acari: Ixodidae) [PDF]

open access: yes, 2008
Background Ticks are obligate blood feeders. The midgut is the first major region of the body where blood and microbes ingested with the blood meal come in contact with the tick's internal tissues.
Daniel E Sonenshine   +2 more
core   +4 more sources

Secreted cystatins decrease proliferation and enhance apoptosis of human leukemic cells

open access: yesFEBS Open Bio, 2020
Cysteine proteases are implicated in proteolysis events favoring cancer cell growth, spread, and death by apoptosis. Herein, we have studied whether the net growth and survival of the leukemic cell lines Jurkat, U937, and HL‐60 are affected by external ...
Samar Hunaiti   +4 more
doaj   +1 more source

Transcript profiling of serine- and cysteine protease inhibitors in Triticum aestivum varieties with different drought tolerance [PDF]

open access: yes, 2016
A high number of protease inhibitors (PI) have been identified in diverse plant species but information about their role in plant stress responses is still fragmentary.
Kirova, E.   +3 more
core   +1 more source

Cystatin C in Alzheimer's disease [PDF]

open access: yesFrontiers in Molecular Neuroscience, 2012
Changes in expression and secretion levels of cystatin C (CysC) in the brain in various neurological disorders and in animal models of neurodegeneration underscore a role for CysC in these conditions. A polymorphism in the CysC gene (CST3) is linked to increased risk for Alzheimer's disease (AD).
Kaur, Gurjinder, Levy, Efrat
openaire   +3 more sources

Analysis of the usefulness and benefits of ultrafiltration in cardiorenal syndrome: A systematic review

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1194-1202, April 2025.
Abstract Aims Cardiac decompensation in cardiorenal syndrome (CRS) results in systemic congestion usually treated with diuretics. When despite high doses of diuretics, response is poor, ultrafiltration (UF) appears to be a useful and safe technique.
Borja Guerrero Cervera   +12 more
wiley   +1 more source

Comparison of proteins with anti-influenza virus effects in parotid and submandibular-sublingual saliva in humans

open access: yesBMC Oral Health, 2022
Background Saliva possesses antiviral activity, with submandibular-sublingual (SMSL) saliva having higher antiviral activity than parotid saliva.
Kenkichi Yamamoto, Shinji Yamamoto
doaj   +1 more source

Cystatins and cancer

open access: yesFrontiers in Bioscience, 2009
Cystatins are natural cysteine protease inhibitors which belong to a superfamily of proteins with wide occurrence in tissues. The cystatins have been shown to play multiple roles in normal and disease processes. In many different cancers the cathepsins, enzymes inhibited by cystatins, are elevated and participate in tumor growth and invasion.
openaire   +2 more sources

Cystatin 11: A New Member of the Cystatin Type 2 Family [PDF]

open access: yesEndocrinology, 2002
Cystatin (CST)11, a novel member of the CST type 2 family of cysteine protease inhibitors, was identified in Macaca mulatta epididymis by subtractive hybridization cloning. The human CST11 gene on chromosome 20p11.2 is located near three other CST genes expressed predominantly in the male reproductive tract.
Katherine G, Hamil   +11 more
openaire   +2 more sources

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

open access: yesEpilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola   +3 more
wiley   +1 more source

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