Results 81 to 90 of about 5,771 (244)

Cell Cycle- and Cancer-Associated Gene Networks Activated by Dsg2: Evidence of Cystatin A Deregulation and a Potential Role in Cell-Cell Adhesion [PDF]

, 2015
This work was supported by grants from the National Institutes of Health (Mahoney, R01AR056067; Riobo, RO1 GM088256). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the ...
A Pavlova, A Rinne, Abhilasha Gupta, AC Steven, AG Barber, AJ Barrett, AJ Merritt, AL Krunic, B Ruffell, B Vray, BD Gelb, BS Parker, BS Sorenson, C Toomes, CC Bitu, D Brennan, D Brennan, D Brennan, D Brennan, D Brennan, D Lazić, Daniela Nitoiu, David P. Kelsell, DC Blaydon, DK Scott, Donna Brennan-Crispi, E Delva, E Hartlieb, E Hartlieb, EP Parrish, F Galbiati, FW Tsui, G Petrof, G. Dubin, H Kurzen, H Takahashi, H Takahashi, H Takahashi, JG Zettergren, Johanna M Brandner, JS Morey, K Biedermann, K Iwatsuki, KJ Green, L Foghsgaard, LA Pennacchio, M Amagai, M Bilodeau, M Ishida, M Pasdar, M Strauss, M Yashiro, MG Mahoney, MG Mahoney, MR Kuracha, MT Teh, MW Butler, Mỹ G. Mahoney, Natalia A. Riobo, ND Rawlings, P Hawley-Nelson, P Strojan, S Estrada, S Kavaklieva, S Magister, SA Keim, SA Mani, Sankar Addya, T Kuopio, T Takai, U Galderisi, UA Nuber, VL Battula, WM Brown, Y Vasilopoulos   +74 more
core   +3 more sources

When Blood Proteins Reveal What Transcripts Miss: Immune Cell Priming and the Road to Prognostic Biomarkers in Lupus

Arthritis &Rheumatology, EarlyView.
Ioannis Parodis
wiley   +1 more source

Outcomes and adverse effects of teduglutide treatment with periodic withdrawal in pediatric short bowel patients

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives We evaluated the efficacy and safety of teduglutide in a real‐world cohort in which national reimbursement policies required treatment interruptions. The primary outcomes were reduction in parenteral support (PS) and treatment‐related adverse effects, and the secondary outcome was the impact of the mandated withdrawal periods ...
Riikka Gunnar, Annika Mutanen, Mikko P. Pakarinen, Laura Merras‐Salmio   +3 more
wiley   +1 more source

Innate secretory immunity in response to laboratory stressors that evoke distinct patterns of cardiac autonomic activity [PDF]

, 2000
Mucosal surfaces are covered by the secretory proteins of the exocrine glands, which provide a first line of innate defense from infections. The release of these secretory proteins is, in theory, sensitive to modulation by psychosocial stress.
Bosch, JA, Geus, E.J.C. de, Hoogstraten, J., Nieuw Amerongen, A. van, Veerman, E.C.I.   +4 more
core   +2 more sources

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

A91

EJC Supplements, 2015
The research for procathepsin B and endogenous inhibitors of cysteine proteases in tumor markers of human reproductive system is important for early diagnostics of cancer.
E. Gashenko, V. Lebedeva, E. Tsykalenko, G. Russkikh, I. Brak, T. Korolenko   +5 more
doaj   +1 more source

Nitric oxide (NO) regulates the expression of single-domain cystatins in glycine max (soybean) [PDF]

, 2013
Plant cystatins inhibit cysteine proteases and are important in regulating plant development and plant responses to biotic and abiotic stress. Furthermore, nitric oxide plays a signaling role in regulating plant responses to developmental processes ...
Adams, Ruqaiyah, Keyster, Marshall, Klein, Ashwil, Ludidi, Ndiko   +3 more
core   +1 more source

Significant modifications of the salivary proteome potentially associated with complications of Down syndrome revealed by top-down proteomics

, 2013
People with Down syndrome, a frequent genetic disorder in humans, have increased risk of health problems associated with this condition. One clinical feature of Down syndrome is the increased prevalence and severity of periodontal disease in comparison ...
Cabras, Tiziana, Castagnola, M, Giuca M., R, Iavarone, F, Messana, Irene, Montaldo, C, Pisano, E, Zampino, G   +7 more
core   +1 more source

Mapping local structural perturbations in the native state of stefin B (cystatin B) under amyloid forming conditions [PDF]

, 2012
Unlike a number of amyloid-forming proteins, stefins, and in particular stefin B (cystatin B) form amyloids under conditions where the native state predominates.
Ajda eTaler-Vercic, Andrea M Hounslow, Carrie-anne eSharma, Eva eZerovnik, Gareth J Morgan, Jonathan P Waltho, Jonathan P Waltho, Matthew J Cliff, Peter J Davis, Robert eParamore, Rosemary Ann Staniforth   +10 more
core   +2 more sources

Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang, Teng‐Fei Li, Tian‐Yu Wang, Huan‐Hai Liu   +3 more
wiley   +1 more source