Results 21 to 30 of about 11,945 (263)

The Role of Cysteine Peptidases in Hematopoietic Stem Cell Differentiation and Modulation of Immune System Function

Frontiers in Immunology, 2021
Cysteine cathepsins are primarily involved in the degradation and recycling of proteins in endo-lysosomal compartments but are also gaining recognition as pivotal proteolytic contributors to various immune functions.
Milica Perišić Nanut, Urša Pečar Fonović, Tanja Jakoš, Janko Kos, Janko Kos   +4 more
doaj   +1 more source

Cystatin C and cystatin SN as possible soluble tumor markers in malignant uveal melanoma

Radiology and Oncology, 2021
The aim of the study was to determine the concentration of endogenous cystatin C and cystatin SN, as potential tumor biomarkers, in the serum and biological fluids of the eye in both healthy controls and patients with uveal melanoma.
Dikovskaya Maria A., Russkikh Galina S., Loktev Konstantin V., Johnston Thomas P., Gevorgyan Margarita M., Voronina Natalya P., Chernykh Valery V., Trunov Alexander N., Korolenko Tatiana A.   +8 more
doaj   +1 more source

The Cysteine Protease–Cysteine Protease Inhibitor System Explored in Soybean Nodule Development

Agronomy, 2013
Almost all protease families have been associated with plant development, particularly senescence, which is the final developmental stage of every organ before cell death.
Marian Dorcas Quain, Karl Kunert, Christine Helen Foyer, Ignatious Ncube, Matome Eugene Makgopa, Stefan van Wyk, Magdeleen du Plessis, Urte Schlüter, Barend Juan Vorster   +8 more
doaj   +1 more source

The Influence of (Poly)phenol Intake in Saliva Proteome: Short- and Medium-Term Effects of Apple

Foods, 2023
The relationship between salivary proteome and dietary habits was studied in previous works, where a relationship between salivary proteins like cystatins and polyphenol/tannin levels in diet was observed.
Teresa Louro, Laura Carreira, Inês Caeiro, Carla Simões, Sara Ricardo-Rodrigues, Ana Elisa Rato, Fernando Capela e Silva, Henrique Luís, Pedro Moreira, Elsa Lamy   +9 more
doaj   +1 more source

Cysteine proteinases and cystatins

Brazilian Archives of Biology and Technology, 2003
This review describeds the definition, localization, functions and examples of cysteine proteinases and their protein inhibitors in vertebrate, non-vertebrate animals and plants. These inhibitors are related with defense mechanisms of plant against pests.
Adeliana S. Oliveira, José Xavier-Filho, Maurício P. Sales   +2 more
doaj   +1 more source

P43

EJC Supplements, 2015
Cystatins are natural endogenous inhibitors of cysteine proteases universally involved into development of different tumors. Tumor growth and metastazing include increased consumption of these inhibitors, followed by decreased level of cystatins and ...
M. Dikovskaya, T. Korolenko, A. Trunov
doaj   +1 more source

Protease Inhibitors in Tick Saliva: The Role of Serpins and Cystatins in Tick-host-Pathogen Interaction

Frontiers in Cellular and Infection Microbiology, 2017
The publication of the first tick sialome (salivary gland transcriptome) heralded a new era of research of tick protease inhibitors, which represent important constituents of the proteins secreted via tick saliva into the host.
Jindřich Chmelař, Jan Kotál, Jan Kotál, Helena Langhansová, Helena Langhansová, Michail Kotsyfakis   +5 more
doaj   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Differential Effect of Novel Plant Cystatins on the Adhesive Behaviour of Normal and Cancer Breast Cells [PDF]

International Journal Bioautomation
In the present work, we have investigated a novel recombinant cystatin dgECP1 and its mutant form, dgECP1m1, focused on their impact on the adhesive behaviour of two breast cell lines: the cancerous, MDA-MB-231, and the normal, MCF-10A.
Kamelia Hristova-Panusheva, Milena Keremidarska-Markova, Natalia Krasteva   +2 more
doaj   +1 more source

TcCYPR04, a Cacao Papain-Like Cysteine-Protease Detected in Senescent and Necrotic Tissues Interacts with a Cystatin TcCYS4. [PDF]

PLoS ONE, 2015
The interaction amongst papain-like cysteine-proteases (PLCP) and their substrates and inhibitors, such as cystatins, can be perceived as part of the molecular battlefield in plant-pathogen interaction.
Thyago Hermylly Santana Cardoso, Ana Camila Oliveira Freitas, Bruno Silva Andrade, Aurizangela Oliveira de Sousa, André da Silva Santiago, Daniela Martins Koop, Karina Peres Gramacho, Fátima Cerqueira Alvim, Fabienne Micheli, Carlos Priminho Pirovani   +9 more
doaj   +1 more source