Results 51 to 60 of about 116 (116)

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Furosemide‐hydration matching with RenalGuard® in decompensated heart failure: an alternative way to use diuretics and saline

ESC Heart Failure, EarlyView.
Massimo Mapelli, Filippo Maria Rubbo, Jeness Campodonico, Nicola Cosentino, Giancarlo Marenzi, Valentina Mantegazza, Filippo Trombara, Mateusz Sokolski, Piotr Ponikowski, Piergiuseppe Agostoni   +9 more
wiley   +1 more source

Actinidia spp. (Kiwifruit): A Comprehensive Review of Its Nutraceutical Potential in Disease Mitigation and Health Enhancement

Food Frontiers, EarlyView.
Nutraceutical Potential in Disease Mitigation and Health Enhancement of Actinidia spp. (Kiwifruit) ABSTRACT This review offers an in‐depth exploration of the Actinidia species (kiwifruit) nutritional composition, the pivotal role of its primary bioactive compounds, and their potential applications across the aforementioned health concerns. Furthermore,
Allah Rakha, Nida Rehman, Rimsha Anwar, Hina Rasheed, Roshina Rabail, Zuhaib F. Bhat, Amin Mousavi Khaneghah, Rana Muhammad Aadil   +7 more
wiley   +1 more source

Pharmacokinetic Characterization of Iopamidol and Iohexol for Optimizing Measured Glomerular Filtration Rate Assessment in Clinical Practice and Drug Development

The Journal of Clinical Pharmacology, EarlyView.
Abstract Accurate kidney function assessment supports healthcare and clinical decision‐making in practice and drug development. Measured glomerular filtration rate (mGFR) via iohexol clearance is the gold standard, but cost, supply issues, and logistical challenges limit its clinical use.
Levi Hooper, Michael Heung, Lu Wang, Aleksas Matvekas, Radin Alikhani, Michael T. Kenes, Kathleen A. Stringer, Bruce A. Mueller, Manjunath P. Pai   +8 more
wiley   +1 more source

Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta, Matt Hall, Benjamin Masserano, Averi Wilson, Katherine Johnson, Clifford Chen, Lasya Challa, Harita Katragadda, Vineeta Mittal   +8 more
wiley   +1 more source

Evaluation of Pediatric and Young Adult Cancer Survivors at Risk of Long‐Term Kidney Complications

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nephrotoxic chemotherapy, nephrectomy, abdominal radiotherapy exposure, and the presence of kidney or pelvic tumors are risk factors associated with long‐term kidney complications. This study aimed to determine the prevalence of long‐term kidney complications in patients who survived pediatric and young adult cancer and were exposed
Ahmed Zeid, Sara Delap, Claudia Mosquera Vasquez, Randal S. Olshefski, Joseph R. Stanek, Lory Guthrie, Diana Zepeda‐Orozco   +6 more
wiley   +1 more source

The Omics‐Driven Machine Learning Path to Cost‐Effective Precision Medicine in Chronic Kidney Disease

PROTEOMICS, EarlyView.
ABSTRACT Chronic kidney disease (CKD) poses a significant and growing global health challenge, making early detection and slowing disease progression essential for improving patient outcomes. Traditional diagnostic methods such as glomerular filtration rate and proteinuria are insufficient to capture the complexity of CKD.
Marta B. Lopes, Roberta Coletti, Flore Duranton, Griet Glorieux, Mayra Alejandra Jaimes Campos, Julie Klein, Matthias Ley, Paul Perco, Alexia Sampri, Aviad Tur‐Sinai   +9 more
wiley   +1 more source

PROTEINASE INHIBITORS | Cystatins

, 2006
The cystatins comprise a superfamily of proteins related primarily by virtue of DNA and amino acid sequence homology. The superfamily consists so far of four distinct types of molecules ranging from the simpler low-molecular-weight type I and II cystatins, which function primarily to inhibit lysosomal cysteine proteinases (CPs), to the higher-molecular-
openaire   +1 more source

Establishment of a Protocol for CE‐MS Based Peptidome Analysis of Human Saliva

PROTEOMICS, EarlyView.
ABSTRACT Proteins and peptides indicate physiological or pathological states and are investigated to identify markers to scrutinize health and disease surveillance. Saliva contains many proteins and peptides that could serve as biomarkers, offering a potential noninvasive approach for disease detection.
Carl‐Johan Törnhage, Björn Peters, Agnieszka Latosinska, Ioanna K. Mina, Marika Mokou, Harald Mischak, Justyna Siwy   +6 more
wiley   +1 more source

Plasma POSTN Derived From Bile Proteome Is a Promising Biomarker for Cholangiocarcinoma With Efficacy Comparable and Complementary to CA19.9

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n 
Lichieh Julie Chu, Chia‐Jung Tsai, Chun‐Chun Chien, Yung‐Chin Hsiao, Jau‐Song Yu, Jun‐Yi Tsai, Ta‐Sen Yeh   +6 more
wiley   +1 more source