Results 61 to 70 of about 11,945 (263)

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

open access: yesEpilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola   +3 more
wiley   +1 more source

A91

open access: yesEJC Supplements, 2015
The research for procathepsin B and endogenous inhibitors of cysteine proteases in tumor markers of human reproductive system is important for early diagnostics of cancer.
E. Gashenko   +5 more
doaj   +1 more source

Dyslipidemia and serum cystatin C levels as biomarker of diabetic nephropathy in patients with type 2 diabetes mellitus [PDF]

open access: gold, 2023
Tadesse Asmamaw Dejenie   +17 more
openalex   +1 more source

A two‐sample Mendelian randomization study and mediation analysis exploring the link between cathepsins and epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective This study aims to investigate the causal relationship between cathepsins and epilepsy, using Mendelian randomization (MR) and mediation analysis. Methods Publicly accessible summary statistics on epilepsy were obtained from FinnGen and the International League Against Epilepsy Consortium.
Huaiyu Sun   +7 more
wiley   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka   +4 more
wiley   +1 more source

Phylogenomic analysis of the cystatin superfamily in eukaryotes and prokaryotes

open access: yesBMC Evolutionary Biology, 2009
Background The cystatin superfamily comprises cysteine protease inhibitors that play key regulatory roles in protein degradation processes. Although they have been the subject of many studies, little is known about their genesis, evolution and functional
Turk Vito, Kordiš Dušan
doaj   +1 more source

Crouching Tiger, Hidden Protein: Searching for Insecticidal Toxins in Venom of the Red Tiger Assassin Bug (Havinthus rufovarius)

open access: yesToxins, 2020
Assassin bugs are venomous insects that prey on other arthropods. Their venom has lethal, paralytic, and liquifying effects when injected into prey, but the toxins responsible for these effects are unknown.
Laura C. Wait   +2 more
doaj   +1 more source

Clinical Relevance and Diagnostic Utility of Standard Serum Biomarkers in Advanced Chronic Kidney Disease: A Single‐Center Observational Study From Bangladesh

open access: yesiLABMED, EarlyView.
This study evaluated conventional and emerging biochemical markers for assessing chronic kidney disease (CKD) progression in Bangladeshi patients elevated serum uric acid and parathyroid hormone levels, along with reduced eGFR, vitamin D, and albumin levels, were significantly associated with CKD, highlighting their potential as cost‐effective early ...
Fazlul Haque   +13 more
wiley   +1 more source

Renal function impairment in children with intestinal failure receiving parenteral nutrition: A descriptive cohort study

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Children with intestinal failure are at risk for kidney dysfunction; however, the contributing factors are not well established. We aimed to describe risk factors associated with glomerular and tubular renal dysfunction in children with intestinal failure.
Amanda M. Braga da Mata   +7 more
wiley   +1 more source

Innate immune response in brain, NF-kappa B signaling and cystatins

open access: yesFrontiers in Molecular Neuroscience, 2015
Recently several reports have demonstrated that innate immune response and inflammation have an important role in major neurodegenerative diseases.
Natasa eKOPITAR-JERALA
doaj   +1 more source

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