Results 81 to 90 of about 116 (116)

Contemporary Perspectives on Chronic Renal Disorders

open access: yesChronic Diseases and Translational Medicine, Volume 11, Issue 2, Page 89-104, June 2025.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok   +5 more
wiley   +1 more source

Neutrophil extracellular traps in cancer: From mechanisms to treatments

open access: yesClinical and Translational Medicine, Volume 15, Issue 6, June 2025.
Neutrophil extracellular traps are intricately linked to the tumor microenvironment and play a crucial role in tumorigenesis, metastasis, and related complications. Consequently, NETs‐based tumor biomarkers and therapeutic strategies warrant significant attention.
Yifan Wang   +5 more
wiley   +1 more source

Design and rationale of the eLym™ System for Decompensation of Excess Lymphatic Fluid via the Thoracic Duct in Acute Heart Failure (DELTA‐HF)

open access: yesESC Heart Failure, Volume 12, Issue 3, Page 1719-1726, June 2025.
Abstract Aims The interstitial space is the major compartment in which the excess fluid is located, forming peripheral congestion in acute decompensated heart failure (ADHF). The lymphatic system is responsible for the constant drainage of the compartment.
Jan Biegus   +12 more
wiley   +1 more source

Validation of a biomarker‐based mortality score for cardiogenic shock patients: Comparison with a clinical risk score

open access: yesESC Heart Failure, Volume 12, Issue 3, Page 2157-2165, June 2025.
Abstract Aims Cardiogenic shock (CS) is the deadliest manifestation of acute heart failure, with persistently high mortality rates and a lack of recent therapeutic breakthroughs. Accurate risk prediction is crucial in clinical decision‐making and the design of future clinical trials.
Elina Hynninen   +14 more
wiley   +1 more source

Sex‐specific associations of Roseburia with uric acid metabolism and hyperuricemia risk in females

open access: yesiMetaOmics, Volume 2, Issue 2, June 2025.
Researchers recruited 623 participants, including 270 females, and used 16S rDNA sequencing to investigate gender differences in hyperuricemia. In healthy females, Roseburia was enriched, positively correlating with estrogen and negatively with uric acid, suggesting it is a potential biomarker affecting uric acid levels in females.
Zhihan Yang   +8 more
wiley   +1 more source

Prevalence and Risk Factors for Augmented Renal Clearance in Neurocritical Ill Patients

open access: yesJournal of Clinical Laboratory Analysis, Volume 39, Issue 11, June 2025.
Augmented renal clearance is prevalent in critically neurological patients. Age is likely to significantly influence renal clearance in this population, especially patients with low Scr and cystatin C levels should be given more attention. ABSTRACT Background Augmented renal clearance (ARC) refers to a phenomenon in critically ill patients ...
Xiangru Ye   +11 more
wiley   +1 more source

Sarcopenia, Muscle Mass and Protein Intake in Adults Older Than 65 Years After Earlier Bariatric Surgery

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 3, June 2025.
ABSTRACT Background Metabolic and bariatric surgery (MBS) is a proven treatment for obesity. Yet weight loss is accompanied by loss of muscle which may predispose to sarcopenia. The prevalence of low muscle mass in older adults after MBS remains unexplored, even though this group is more vulnerable to sarcopenia.
Gabriël Eksteen   +7 more
wiley   +1 more source

Sensory Nerve Action Potential Analysis in a Cohort of Patients With Spinal Muscular Atrophy Aged 12 Years and Older

open access: yesMuscle &Nerve, Volume 71, Issue 6, Page 1016-1024, June 2025.
ABSTRACT Introduction/Aims Survival Motor Neuron 1 (SMN1)‐related spinal muscular atrophy (SMA) is characterized by α‐motor neuron degeneration, with sensory function assumed to be clinically preserved. However, recent studies in severely affected patients and animal models have challenged this view.
Leandra A. A. Ros   +7 more
wiley   +1 more source

Effect of creatine monohydrate on motor function in children with facioscapulohumeral muscular dystrophy: A multicenter, randomized, double‐blind placebo‐controlled crossover trial

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 6, Page 341-351, June 2025.
Abstract Background Facioscapulohumeral muscular dystrophy (FSHD) is a rare, progressive muscle disease with no available disease‐modifying therapy. Creatine monohydrate (CrM) has been shown to improve muscle strength in individuals with muscular dystrophies but has not been tested in young people with FSHD.
Ian R. Woodcock   +13 more
wiley   +1 more source

Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments

open access: yesAging Cell, Volume 24, Issue 6, June 2025.
The association of the aging scores with the clinical covariates suggests increased inflammation, strong predisposition to iron deficiency anemia, decline in muscle mass, and renal and hepatic functions with accelerated aging. ABSTRACT The study of biomarkers in biofluids and tissues expanded our understanding of the biological processes that drive ...
R. Moaddel   +17 more
wiley   +1 more source

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