Results 91 to 100 of about 120,191 (200)
Genetic Susceptibility to Periodontitis
Journal of Periodontal Research, EarlyView.Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley +1 more source
Roles of cysteine cathepsins in intestinal homeostasis
, 2012 Cysteine cathepsins are endo-lysosomal proteases expressed in a variety of cells and tissues, including the gastrointestinal tract. Trafficking and localization studies have changed the classical view of cysteine cathepsins as enzymes acting only ...
Arampatzidou, Maria
core +1 more source
The Role of Oxidative Stress in Periodontitis
Journal of Periodontal Research, EarlyView.Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
The International Journal of Biological Markers, 2000 Cathepsins B, H and L have been shown to participate in processes of tumor growth, vascularization, invasion and metastasis. Their levels in tumor tissue extracts can provide useful clinical information to predict disease-free and overall survival in ...
J. Kos, B. Werle, T. Lah, N. Brunner
doaj +1 more source
Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications
Journal of Periodontal Research, EarlyView.Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu +4 more
wiley +1 more source
Cysteine cathepsins are not involved in Fas/CD95 signalling in primary skin fibroblasts [PDF]
, 2007 The potential role of cysteine cathepsins, especially cathepsin B, in Fas/CD95-induced apoptosis was investigated using wild-type and cathepsin B-deficient primary skin fibroblasts.
Reinheckel, Thomas +6 more
core +1 more source
Role of cathepsin S In periodontal wound healing–an in vitro study on human PDL cells
BMC Oral Health, 2018 Background Cathepsin S is a cysteine protease, which is expressed in human periodontal ligament (PDL) cells under inflammatory and infectious conditions.
Svenja Memmert +11 more
doaj +1 more source
Parasites & Vectors, 2008 Background Ticks are vectors for a variety of viral, bacterial and parasitic diseases in human and domestic animals. To survive and reproduce ticks feed on host blood, yet our understanding of the intestinal proteolytic machinery used to derive ...
Mareš Michael +6 more
doaj +1 more source
Experimental Physiology, EarlyView.Abstract Ageing is associated with loss of skeletal muscle mass and strength (sarcopenia) and disrupted redox homeostasis. Redox signalling is essential for muscle adaptation, yet the mechanisms by which ageing disrupts cysteine‐based regulation are poorly defined. The drivers of site‐specific reactivity and signalling specificity in aged muscle remain
Ufuk Ersoy, Malcolm J. Jackson
wiley +1 more source