Results 111 to 120 of about 219,552 (223)
British Journal of Pharmacology, Volume 183, Issue 10, Page 2236-2255, May 2026.Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi +19 more
wiley +1 more source
Two α subunits and one β subunit of meprin zinc-endopeptidases are differentially expressed in the zebrafish Danio rerio [PDF]
, 2017 Meprins are members of the astacin family of metalloproteases expressed in epithelial tissues, intestinal leukocytes and certain cancer cells. In mammals, there are two homologous subunits, which form complex glycosylated disulfide-bonded homo- and ...
Becker-Pauly, Christoph +4 more
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Modeling Synaptic Maturation From Growth Cone to Synapse in Human Organoids
Journal of Neurochemistry, Volume 170, Issue 5, May 2026.Synapses are implicated in several neurological disorders and psychiatric diseases. The emergence and wide use of neural organoids provide a new opportunity to study human synapses in healthy and disease settings. Therefore, we developed a simple method for the enrichment of synaptosomes and growth cone particles from forebrain organoids. The method is
Marie S. Øhlenschlæger +16 more
wiley +1 more source
Processing and release of endogenous immunogenic peptide signals
The Plant Journal, Volume 126, Issue 3, May 2026.SUMMARY In both animals and plants, small secreted peptides known as cytokines and phytocytokines mediate local and systemic communication during immune and stress responses. These signaling molecules are typically synthesized as inactive precursors that require proteolytic processing to become active.
Maurice Koenig +3 more
wiley +1 more source
The Plant Journal, Volume 126, Issue 3, May 2026.SUMMARY Lentil is an important legume crop with significant nutritional value, playing a pivotal role in environmentally sustainable agricultural systems. The lentil whole‐genome resequencing data have not been reported. In this study, we re‐sequenced a total of 238 Lens accessions, including 112 cultivated lentils, 71 landraces, and 55 wild species ...
Yu Ma +11 more
wiley +1 more source
Cloning, sequencing and extracellular expression of the alkaline protease gene from Bacillus stearothermophilus F1 [PDF]
, 2001 The gene of a highly thermostable alkaline protease was amplified from Bacillus stearothermophilus F1 by polymerase chain reaction using consensus primers based on the sequences of serine protease genes from related species.
Fu, Zhibiao
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The model of proteolysis [PDF]
, 2010 This document presents the original approach for estimating parameters of proteolysis process. Data used to fit the model are taken from mass spectrometric experiments. For parameters estimation the Levenberg-Marquadt algorithm is used.
Anna Gambin, Piotr Dittwald
core +1 more source
Cysteine-proteases and cystatins from barley: molecular and functional characterization in housekeeping and defense processes [PDF]
, 2011 Plant cysteine-proteases (CysProt) represent a well-characterized type of proteolytic enzymes that fulfill tightly regulated physiological functions (senescence and seed germination among others) and defense roles. This article is focused on the group of
Cambra Marin, Ines +4 more
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Celiac Disease: A Challenging Disease for Pharmaceutical Scientists [PDF]
, 2018 : Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten-containing grains that affects ~1% of the white ethnic population.
Fuhrmann, Gregor +2 more
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