Results 11 to 20 of about 56,630 (276)
Indispensable residue for uridine binding in the uridine-cytidine kinase family
Biochemistry and Biophysics Reports, 2017 Uridine-cytidine kinase (UCK), including human UCK2, are a family of enzymes that generally phosphorylate both uridine and cytidine. However, UCK of Thermus thermophilus HB8 (ttCK) phosphorylates only cytidine.
Ryoji Masui, Takato Yano, Kenji Fukui
exaly +4 more sources
Fermentation, 2022 Cytidine is an antiviral and anticancer drug intermediate, its primary method of manufacture being fermentation. Uridine-cytidine kinase (UCK) catalyzes the reverse process of phosphorylation of cytidine to produce cytidylic acid, which influences ...
Fengmin Liu +5 more
doaj +2 more sources
Association of Inosine and Cytidine [PDF]
Biophysical Journal, 1971 A rigorous theory for the analysis of an associating system involving two different monomer units, which may also undergo self-association, has been developed.
Kolinski, R., Magar, M.E., Steiner, R.F.
core +3 more sources
ADP-Ribosylation of Cytidine: A Novel Nucleic Acid Modification Reversed by NADAR Hydrolases [PDF]
ToxinsADP-ribosylation of nucleic acids is a modification found in both eukaryotes and bacteria, where it contributes to genome maintenance but can also serve as a toxic mechanism used by bacterial toxins to disrupt essential cellular processes.
Petra Mikolčević +6 more
doaj +2 more sources
Efficient deamination of 5-methylcytidine and 5-substituted cytidine residues in DNA by human APOBEC3A cytidine deaminase. [PDF]
PLoS ONE, 2013 Deamination of 5-methylcytidine (5MeC) in DNA results in a G:T mismatch unlike cytidine (C) deamination which gives rise to a G:U pair. Deamination of C was generally considered to arise spontaneously.
Rodolphe Suspène +3 more
doaj +2 more sources
The photophysics of protonated cytidine and hemiprotonated cytidine base pair: A computational study
Photochemistry and Photobiology, 2023 9 pags., 7 figs., 2 tabs.We here study the effect that a lowering of the pH has on the excited state processes of cytidine and a cytidine/cytidine pair in solution, by integrating time-dependent density functional theory and CASSCF/CASPT2 calculations ...
Improta, Roberto +3 more
core +4 more sources
Enhancing cytidine biosynthesis by coupling minicell-forming morphology with biofilm-based fermentation [PDF]
Synthetic and Systems BiotechnologyCytidine is an important nucleoside in the pharmaceutical and biotechnology fields. To improve its biosynthesis efficiency, this study proposes a strategy that integrates minicell-forming recombinant strains with biofilm-based fermentation.
Di Zhang +3 more
doaj +2 more sources
Partial purification of cytidine deaminase from protoscoleces of Echinococcus granulosus [PDF]
Kirkuk Journal of Science, 2015 Cytidine deaminase (EC 3.5.4.5) has been partially purified from protoscoleces of Echinococcus granulosus by gel filteration chromatography using Sephadex G200 .The molecular weight of the enzyme determined by gel filteration was about 82000 dalton with ...
Husain F. Hassan, Jenan A.Saber
doaj +3 more sources
An enzymatic assay for high-throughput screening of cytidine-producing microbial strains.
PLoS ONE, 2015 Cytidine is an industrially useful precursor for the production of antiviral compounds and a variety of industrial compounds. Interest in the microbial production of cytidine has grown recently and high-throughput screening of cytidine over-producers is ...
Huina Dong +5 more
doaj +2 more sources
Beilstein Journal of Organic Chemistry, 2014 Over the past 20 years, the generation of functional RNAs by in vitro selection has become a standard technique. Apart from aptamers for simple binding of defined ligands, also RNAs for catalysis of chemical reactions have been selected.
Nico Rublack, Sabine Müller
doaj +2 more sources