Results 91 to 100 of about 1,700,978 (266)

Effect of EGb761 on light-damaged retinal pigment epithelial cells

open access: yesInternational Journal of Ophthalmology, 2014
AIM:To investigate the protective mechanism of Gingko Biloba extract (EGb761) on the ability of retinal pigment epithelial (RPE) cells to resist light-induced damage in a comparative proteomics study.METHODS:Human RPE cells (ARPE-19) were randomly ...
Yun-Yun Zhou   +7 more
doaj   +1 more source

Ultrasound‐Responsive 4D Bioscaffold for Synergistic Sonopiezoelectric‐Gaseous Osteosarcoma Therapy and Enhanced Bone Regeneration

open access: yesAdvanced Science, EarlyView.
An acoustic‐responsive therapeutic platform for synergistic sonopiezoelectric‐gaseous osteosarcoma therapy and bone regeneration is fabricated through the joint loading of few‐layer black phosphorus nanosheets and S‐Nitroso‐L‐glutathione onto the 3D‐printed bioactive glass scaffolds.
Haoyu Fang   +8 more
wiley   +1 more source

A DNA-based approach to infer species diversity of larvae and adults from the white grub genus Phyllophaga (Coleoptera: Scarabeidae)

open access: yesFrontiers in Insect Science
Scarabaeoidea is a diverse and widely distributed insect group; many are agricultural pests including species within the genus Phyllophaga. Species diversity studies in this taxonomic group are done mainly using morphological identification.
Ariel W. Guzmán-Franco   +5 more
doaj   +1 more source

Engineered Hydrogels for Organoid Models of Human Nonalcoholic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
Nonalcoholic fatty liver disease (NAFLD) is characterized by lipid accumulation and extracellular matrix stiffening. An in vitro NAFLD model is developed using engineered hydrogels (G′ ≈ 1–6 kPa) and iPSC‐derived hepatic organoids. It is demonstrated that higher stiffness can increase lipid droplet accumulation, fibrosis, and metabolic dysregulation ...
Yueming Liu   +11 more
wiley   +1 more source

Phylogeny and high diversity of the Old World cyprinodont, Genus Aphanius (Teleostei, Cyprinodontidae) in the Iranian Plateau

open access: yesFrontiers in Marine Science, 2015
To date, 28 species of Aphanius have been recognized in the World, of which 14 species are described from six endorheic and eight exorheic basins in Iran.
Zeinab Gholami   +3 more
doaj   +1 more source

Photo‐Biomodulation of the Hippocampus Using Near‐Infrared Laser to Enhance Cognitive Function in Mice

open access: yesAdvanced Science, EarlyView.
Here a transcranial photo‐biomodulation approach is developed using near‐infrared (NIR) laser on hippocampus of mice, revealing significant improvements in learning and memory ability of mice under normal and disease conditions. The improvement results from the high‐density cell‐induced NIR local energy deposition, neuronal activation, and axonogenesis
Wei‐Tong Pan   +6 more
wiley   +1 more source

Exposure to Benzo(a)pyrene Enhances Acetaminophen-Induced Liver Injury in Mice at Non-Hepatotoxic Doses

open access: yesScientia Pharmaceutica
Acetaminophen (APAP) is a widely used analgesic, especially for children. Its primary mechanism involves inhibiting cyclooxygenase enzymes and activating the endocannabinoid and TRPV1 systems.
Yina Montero-Pérez   +1 more
doaj   +1 more source

LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells

open access: yesAdvanced Science, EarlyView.
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang   +5 more
wiley   +1 more source

Elastic Deformation of Cellulose/Lignin‐Based Anode for Rejuvenating Aged Mix‐Cultured Electroactive Biofilms

open access: yesAdvanced Science, EarlyView.
A new strategy for revitalizing aged biofilms using the elastic deformation of biomass‐based flexible carbon aerogel is proposed. The elastic deformation removes the nonelectrogenic bacteria and the dead electrogenic bacteria, as well as a lot of loosely bound extracellular polymer materials.
Xue Liu   +15 more
wiley   +1 more source

Molecular phylogenetics of soricid shrews (Mammalia) based on mitochondrial cytochrome b gene sequences: with special reference to the Soricinae

open access: yes, 2006
Molecular phylogeny of soricid shrews (Soricidae, Eulipotyphla, Mammalia) based on 1140 bp mitochondrial cytochrome b gene (cytb) sequences was inferred by the maximum likelihood (ML) method.
S. Ohdachi   +6 more
semanticscholar   +1 more source

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