Cox1 mutation abrogates need for Cox23 in cytochrome c oxidase biogenesis [PDF]
Microbial Cell, 2016 Cox23 is a known conserved assembly factor for cytochrome c oxidase, although its role in cytochrome c oxidase (CcO) biogenesis remains unresolved. To gain additional insights into its role, we isolated spontaneous suppressors of the respiratory growth ...
Richard Dela Cruz +2 more
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Exosome profile and composite indices reflect immune exhaustion in periodontitis [PDF]
Scientific ReportsIntroduction Exosomes are small extracellular vesicles that regulate immune responses, inflammation, and tissue homeostasis. While several exosomal molecules have been investigated individually in periodontitis, a functional characterization based on ...
Marco Bonilla +3 more
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Frontiers in Microbiology, 2017 The thiol-disulfide oxidoreductase DsbA carries out oxidative folding of extra-cytoplasmic proteins by catalyzing the formation of intramolecular disulfide bonds. It has an important role in various cellular functions, including cell division. The purple
Hans-Georg Koch +2 more
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Structurally Mapping Endogenous Heme in the CcmCDE Membrane Complex for Cytochrome c Biogenesis [PDF]
Journal of Molecular Biology, 2018 David Baker +2 more
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In vitro reconstitution reveals major differences between human and bacterial cytochrome c synthases
eLife, 2021 Cytochromes c are ubiquitous heme proteins in mitochondria and bacteria, all possessing a CXXCH (CysXxxXxxCysHis) motif with covalently attached heme. We describe the first in vitro reconstitution of cytochrome c biogenesis using purified mitochondrial ...
Molly C Sutherland +8 more
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Selenite stimulates mitochondrial biogenesis signaling and enhances mitochondrial functional performance in murine hippocampal neuronal cells. [PDF]
PLoS ONE, 2012 Supplementation of selenium has been shown to protect cells against free radical mediated cell damage. The objectives of this study are to examine whether supplementation of selenium stimulates mitochondrial biogenesis signaling pathways and whether ...
Natalia Mendelev +4 more
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mBio, 2023 Heme trafficking is a fundamental biological process, yet its direct study has been hampered due to heme’s tight intracellular regulation, heme cytotoxicity, and the transient nature of trafficking.
Amber L. Grunow +3 more
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Bacterial cytochromes c biogenesis. [PDF]
Genes & Development, 1992 We report the primary sequence analyses of two loci, hel and ccl, whose gene products are required specifically for the biogenesis of c-type cytochromes in the Gram-negative photosynthetic bacterium Rhodobacter capsulatus. Genetic and molecular analyses show that the hel locus contains at least four genes, helA, helB, helC, and orf52, and the ccl locus
D L, Beckman, D R, Trawick, R G, Kranz
openaire +2 more sources
Brain Region Specificity of Mitochondrial Biogenesis and Bioenergetics Response to Nrf2 Knockdown: A Comparison Among Hippocampus, Prefrontal Cortex and Amygdala of Male Rat Brain [PDF]
Brazilian Archives of Biology and Technology, 2017 Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) has been identified as the well-known coordinator of intracellular antioxidant defense system. Herein, we aimed to evaluate the effects of Nrf2 silencing on mitochondrial biogenesis markers peroxisome ...
Solmaz Khalifeh +5 more
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Reperfusion promotes mitochondrial biogenesis following focal cerebral ischemia in rats. [PDF]
PLoS ONE, 2014 BACKGROUND AND PURPOSE: Reperfusion after transient cerebral ischemia causes severe damage to mitochondria; however, little is known regarding the continuous change in mitochondrial biogenesis during reperfusion.
Yuying Xie +4 more
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