Results 191 to 200 of about 42,954 (256)

Cytochrome c oxidase biogenesis, its disorders in childhood

open access: yesBiochimica et Biophysica Acta (BBA) - Bioenergetics, 2010
Zeman, Jiri, Stiburek, Lukas
openaire   +1 more source

Tunnelling Nanotube‐Mediated Lysosome Sharing Promotes Osteocyte Survival via Transcellular Autophagy

open access: yesCell Proliferation, Volume 59, Issue 7, July 2026.
This study provides the first definitive identification of tunnelling nanotubes (TNTs) between cultured osteocytes and shows TNT‐mediated lysosome transfer from healthy to stressed cells, restoring autophagic flux and preventing apoptosis. This discovery of transcellular autophagy reveals a new survival mechanism in osteocytes, offering potential ...
Jinbiao Qiang   +16 more
wiley   +1 more source

The pharmacology of gepants in migraine: A scoping review on mechanisms, clinical applications, and combination strategies

open access: yesHeadache: The Journal of Head and Face Pain, Volume 66, Issue 7, Page 1628-1643, July/August 2026.
Abstract Background Calcitonin gene‐related peptide (CGRP) is a key mediator in migraine pathophysiology, and the development of gepants, novel CGRP receptor antagonists, has expanded therapeutic options for both acute and preventive treatment. This scoping review aims to synthesize current evidence on the pharmacology, clinical applications, safety ...
Luigi Francesco Iannone   +5 more
wiley   +1 more source

Pentatricopeptide repeat proteins in crops: Advances in functional mechanisms and breeding applications

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 7, Page 1973-2000, July 2026.
Pentatricopeptide repeat proteins coordinate nucleus‐organelle communication by modulating RNA metabolism within chloroplasts and mitochondria. This review highlights how they control critical processes like photosynthesis, seed development, fertility restoration, and stress survival in crops, and explores their potential as programmable tools for RNA ...
Mingming Wu   +7 more
wiley   +1 more source

Single‐nuclei RNA sequencing reveals heterogeneity within developing GnRH3 neurons in zebrafish

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 7, July 2026.
Abstract Gonadotropin‐releasing hormone (GnRH) is a central regulator of vertebrate reproduction regulating pituitary gonadotropins. In zebrafish, GnRH3 serves as the hypophysiotropic isoform. Its neurons develop by migrating from the nasal placode to the hypothalamus, forming several distinct subpopulations along the migratory path.
Yalong Sun   +4 more
wiley   +1 more source

Skeletal muscle‐specific myostatin overexpression promotes muscle oxidative capacity and fatigue resistance in transgenic mice

open access: yesExperimental Physiology, Volume 111, Issue 7, Page 3357-3380, 1 July 2026.
Abstract In addition to controlling muscle mass, myostatin may support oxidative metabolism and endurance. Loss of function through gene knockout or post‐natal blockade generally lowers muscle oxidative capacity and increases fatigability. These observations imply that myostatin activation could promote a more oxidative and less fatigable muscle ...
Andy V. Khamoui   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy