Results 171 to 180 of about 41,955 (238)
Stress‐induced switch. Under stress conditions, small extracellular vesicle release shifts from the constitutive ‘torn bag mechanism’ to exocytosis of multivesicular endosomes. https://BioRender.com/xn1pa1e. ABSTRACT The biogenesis of small extracellular vesicles (sEVs) is only partially understood.
Dorina Lenzinger +18 more
wiley +1 more source
In and out of the mitochondrial intermembrane space. [PDF]
van der Schans F +2 more
europepmc +1 more source
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong +8 more
wiley +1 more source
Pangenomics-Driven Reverse Vaccinology for the Discovery of New Vaccine Candidates Against <i>Bordetella pertussis</i>. [PDF]
Abdelouahab M, Idrissa D.
europepmc +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
Mitochondrial dysfunction in neonatal brain injury: from molecular mechanisms to therapeutic interventions. [PDF]
Teng C, Wei J, Zhu Y, Chen A, Chen X.
europepmc +1 more source
ABSTRACT Type 2 diabetes mellitus (T2DM) is a central component of the metabolic syndrome (MetS) and is associated with underlying mitochondrial dysfunction. Disruption of mitochondrial homeostasis impairs cellular energy metabolism and contributes to the overproduction of reactive oxygen species (ROS), leading to oxidative stress, chronic inflammation,
Shanika Reddy +3 more
wiley +1 more source
Organelle regulation of ferroptosis after intracerebral hemorrhage. [PDF]
Zhou N, Du Y, Wang Y, Zhao X, Ju Y.
europepmc +1 more source
Using nanopore metagenomics, this study reveals that anthropogenic pollution drives ecological and functional shifts in coastal microbiomes. Pristine island environments act as stable, Prochlorococcus‐dominated baselines, whereas urban beaches function as hotspots for opportunistic taxa, harbouring a robust genomic potential for xenobiotic degradation ...
Angelo Felipe Barbosa de Oliveira +7 more
wiley +1 more source
Targeting mitochondrial quality control in diabetic kidney disease: emerging therapeutic opportunities. [PDF]
Luo J +5 more
europepmc +1 more source

